Protein Alignment Cyp9h1 and CYP4F11

DIOPT Version :10

• Sequence 1: NP_610820.1
• Gene: Cyp9h1 / 36412
• FlyBaseID: FBgn0033775
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_067010.3
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 114/440 - (25%)
• Similarity: 191/440 - (43%)
• Gaps: 96/440 - (21%)

  Fly   118 LSKSLISLRDGRWKEMRNILTPAF-----------TGSKMRIMYDLIQSCSEEGVIHIQEQLELS 171
            |...|:.....:|...|.:|||||           ....:.||:|..|..:.||
Human   132 LGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEG----------- 185

  Fly   172 QDASIELEMKDYFTRFANDVIATVAFGISINSFRRKDNEFFRIGQAMSRISAWSVVKA------- 229
               |..|:|.::.:....|.:....|....|. :.|.:|:.   .|:..:||: |.|.
Human   186 ---SARLDMFEHISLMTLDSLQKCVFSFESNC-QEKPSEYI---AAILELSAF-VEKRNQQILLH 242

  Fly   230 --MLYALFPRLMKVLR------------IQ----VLDTKNIDYFSSLVTAAMRYRQEHKVVRPDM 276
              .||.|.|...:..|            ||    .|.|:.||.|       ::.:.:.|.:  |.
Human   243 TDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDF-------LKNKAKSKTL--DF 298

  Fly   277 IHLLMEAKQQRLADLSDKSKDELYYSEFTADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTV 341
            |.:|:.:|.:...:|||             :|:.|:...|.|.|.:..:|.|.::.:.|..:|..
Human   299 IDVLLLSKDEDGKELSD-------------EDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEY 350

  Fly   342 QDRLYEEIISVHEELKGQPLTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQK 406
            |::..:|:..:.::.:...:.:|.|.::.:|.|.:.|:||..||.....|.|.||..|.|  |:.
Human   351 QEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPD--GRV 413

  Fly   407 LFSARKGDVLQIPIFSLHHDPENFEDPEFFNPERFADGHALESR---VYMPFGVGPRNCIGNRMA 468
            :   .||.|..|.|..:|::|..:.|||.::|.|| |...::.|   .::||..|||||||...|
Human   414 I---PKGIVCLINIIGIHYNPTVWPDPEVYDPFRF-DQENIKERSPLAFIPFSAGPRNCIGQAFA 474

  Fly   469 LMELKSIVYQLLLNFKLLPA---KRTSRDLLNDIRGHGLKPKNGFWLKFE 515
            :.|:|.::...||:|::||.   .|...:|:       |:.:.|.||:.|
Human   475 MAEMKVVLALTLLHFRILPTHTEPRRKPELI-------LRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	CYP6-like	69..511	CDD:410679	111/434 (26%)
CYP4F11	NP_067010.3	CYP4F	74..515	CDD:410772	112/436 (26%)