DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9h1 and Cyp4f1

DIOPT Version :9

Sequence 1:	NP_610820.1	Gene:	Cyp9h1 / 36412	FlyBaseID:	FBgn0033775	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_062569.2	Gene:	Cyp4f1 / 56266	RGDID:	70926	Length:	524	Species:	Rattus norvegicus

Alignment Length:	456	Identity:	116/456 - (25%)
Similarity:	201/456 - (44%)	Gaps:	91/456 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 HNNIQESILSKS-LISLRD--------------------GRWKEMRNILTPAFTGSKMRIMYDLI 153
            |::|..|||:.| .::|:|                    .:|...|.:|||||   ...|:...:
  Rat   103 HSDIVRSILNASAAVALKDVIFYTILKPWLGDGLLVSAGDKWSRHRRMLTPAF---HFNILKPYV 164

  Fly   154 QSCSEE-GVIHIQEQLELSQDASIELEMKDYFTRFANDVIATVAFGISINSFRRKDNEFFRIGQA 217
            :..::. .::|.:.:..:|:.:| .|:|.::.:....|.:....|....|. :.|.:|:.   .|
  Rat   165 KIFNDSTNIMHAKWKRLISEGSS-RLDMFEHVSLMTLDSLQKCVFSFDSNC-QEKSSEYI---AA 224

  Fly   218 MSRISAWSVVKAMLYALFPRLMKVLRIQVLDTKNIDYFSSLVTAAMRYRQEHKVVRPDMIHLLME 282
            :..:||....:.....||                :|...:|....||:   ||..  :::|...:
  Rat   225 ILELSALVAKRHQQPLLF----------------MDLLYNLTPDGMRF---HKAC--NLVHEFTD 268

  Fly   283 AK-QQRLADLSDKSKDELYYS----------------------EFTADDLLAQCLLFFFAGFEII 324
            |. ::|...|.|:..||...|                      |.:.:|:.|:...|.|.|.:..
  Rat   269 AVIRERRRTLPDQGLDEFLKSKAKSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMFEGHDTT 333

  Fly   325 SSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQPLTYDKLTKMKYLDMVVLEALRKWPPSIST 389
            :|.|.::.:.|..:|..|:|..:|:..:..:...:.:.:|.|.::.:|.|.:.|:||..||....
  Rat   334 ASGLSWILYNLAKHPEYQERCRQEVQELLRDRDPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVI 398

  Fly   390 DRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHHDPENFEDPEFFNPERFADGHALESR--VY 452
            .|.|.|||.|.|  |:.:   .||.:..|.||.:||:|..:.|||.:||.||...:..:|.  .:
  Rat   399 SRCCTQDILLPD--GRTI---PKGIICLISIFGIHHNPSVWPDPEVYNPFRFDPENIKDSSPLAF 458

  Fly   453 MPFGVGPRNCIGNRMALMELKSIVYQLLLNFKLLPAKRTSR---DLLNDIRGHGLKPKNGFWLKF 514
            :||..|||||||...|:.|:|..:...||.|:|||..:..|   :|:       |:.:.|.||:.
  Rat   459 IPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELI-------LRAEGGLWLRV 516

  Fly   515 E 515
            |
  Rat   517 E 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	p450	38..512	CDD:278495	113/451 (25%)
Cyp4f1	NP_062569.2	CYP4F	74..515	CDD:410772	114/452 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900