DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9h1 and Cyp6t1

DIOPT Version :9

Sequence 1:	NP_610820.1	Gene:	Cyp9h1 / 36412	FlyBaseID:	FBgn0033775	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_608457.1	Gene:	Cyp6t1 / 33127	FlyBaseID:	FBgn0031182	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	543	Identity:	152/543 - (27%)
Similarity:	256/543 - (47%)	Gaps:	56/543 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SMIALALFIILLVLL---------------YKWSVAKYDVFSERGVSHEKPWPLIGNIPLKAMIG 53
            |:||.||.:..||||               :.|.:..:..:...||......|.:||: ...:.|
  Fly     6 SLIAAALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFWHWRRLGVPFVPAAPFVGNV-WNLLRG 69

  Fly    54 GMPVLKKMIELH--TKHTGSPVYGIYALRDAVFFVRDPELIKLIGIKEFDHFVNHNSMHNNIQES 116
            ......:..||:  .:..|....||..|.:....:|||.|||.|.:::|..|.:.....:...::
  Fly    70 ACCFGDQFRELYESKEAAGRAFVGIDVLHNHALLLRDPALIKRIMVEDFAQFSSRFETTDPTCDT 134

  Fly   117 ILSKSLISLRDGRWKEMRNILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQLELSQDASIELEMK 181
            :.|::|...:...|:|...|..|.|...|:|.||.|:::..::...|:::  :||...|:|||:|
  Fly   135 MGSQNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQ--KLSGRDSMELEVK 197

  Fly   182 DYFTRFANDVIATVAFGISINSFRRKDNEFFRIGQAMSRISAWSVVKAMLYALFPRLMKVLRIQV 246
            .....|..|:||::||||..:|.:..:.||.|:...::......::.......||||...:...:
  Fly   198 QLCALFTTDIIASLAFGIEAHSLQNPEAEFRRMCIEVNDPRPKRLLHLFTMFFFPRLSHRVGTHL 262

  Fly   247 LD-------TKNIDYFSSLVTAAMRYRQEHKVVRPDMIHLLMEAKQQRLADLSDKSKDELYYSEF 304
            ..       .|::||       .:..|.|....|.|:|.:.::.|:      ::.::..::..:|
  Fly   263 YSEEYERFMRKSMDY-------VLSQRAESGENRHDLIDIFLQLKR------TEPAESIIHRPDF 314

  Fly   305 TADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQPLTYDKLTKM 369
            .|    ||......|||:..||::.|..:||..|.|:||||..|:.:..:..:.:.|:.|.:|.:
  Fly   315 FA----AQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGL 375

  Fly   370 KYLDMVVLEALRKWPPSISTDREC--RQDIDLFDENGQKLFSARKGDVLQIPIFSLHHDPENFED 432
            .||..||.|.||.:||:...||.|  |...||...||...|..|.|..:.|.:..:|.|.:.:.:
  Fly   376 VYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPN 440

  Fly   433 PEFFNPERFADGHALESR------VYMPFGVGPRNCIGNRMALMELKSIVYQLLLNFKLLPAKRT 491
            ||.|:||||    :.|.|      .|:|||.|||.|||..:..:|:|..:..:|.:|::...:||
  Fly   441 PEVFDPERF----SAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERT 501

  Fly   492 SRDLLNDIRGHGLKPKNGFWLKF 514
            ..::..|.:...|...||.:|:|
  Fly   502 LPEMRFDPKAFVLTAHNGTYLRF 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	p450	38..512	CDD:278495	138/490 (28%)
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	128/446 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461028
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900