Protein Alignment Cyp9h1 and CYP4X1

DIOPT Version :9

• Sequence 1: NP_610820.1
• Gene: Cyp9h1 / 36412
• FlyBaseID: FBgn0033775
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_828847.1
• Gene: CYP4X1 / 260293
• HGNCID: 20244
• Length: 509
• Species: Homo sapiens
• Alignment Length: 537
• Identity: 135/537 - (25%)
• Similarity: 242/537 - (45%)
• Gaps: 83/537 - (15%)

  Fly     5 MIALALFIILLVLLYKWSVAKYDVFSERGVSHEKPWPLIGNIPLKAMIG--------GMPVLKKM 61
            :..|||.::..:.||        :..:|.:...:|:|.   .|....:|        .|..|:::
Human    19 VFCLALGLLQAIKLY--------LRRQRLLRDLRPFPA---PPTHWFLGHQKFIQDDNMEKLEEI 72

  Fly    62 IELHTKHTGSPVY-GIYALRDAVFFVRDPELIKLIGIKEFDHFVNHNSMHNNIQESILSKSLISL 125
            ||.:.:  ..|.: |.:   .|.|.:.||:..|.: :...|   ..:.........:|.|.|.:|
Human    73 IEKYPR--AFPFWIGPF---QAFFCIYDPDYAKTL-LSRTD---PKSQYLQKFSPPLLGKGLAAL 128

  Fly   126 RDGRWKEMRNILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQLELSQDASIELEMKDYFTRFAND 190
            ...:|.:.|.:|||.|..:.:: .|..:.:.|.:.::...|::..:||.|:  |:.::....:.|
Human   129 DGPKWFQHRRLLTPGFHFNILK-AYIEVMAHSVKMMLDKWEKICSTQDTSV--EVYEHINSMSLD 190

  Fly   191 VIATVAFGISINSFRRKDNEFFRIGQAMSRISAWSVVKAMLYAL----------------FPRLM 239
            :|...||....|......::.:  .:|:..:|  .::...||:|                |.:|.
Human   191 IIMKCAFSKETNCQTNSTHDPY--AKAIFELS--KIIFHRLYSLLYHSDIIFKLSPQGYRFQKLS 251

  Fly   240 KVLRIQVLDTKNIDYFSSLVTAAMRYRQEHKVVRPDMIHLLMEAKQQRLADLSDKSKDELYYSEF 304
            :||. |..||...:...||....   :|::...|          |.|...|:...:||| ..|.|
Human   252 RVLN-QYTDTIIQERKKSLQAGV---KQDNTPKR----------KYQDFLDIVLSAKDE-SGSSF 301

  Fly   305 TADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQPLTYDKLTKM 369
            :..|:.::...|..||.:.:::|:.::.:.|.|||..|:|..||:..:..:  |..:|:|:|.:|
Human   302 SDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGD--GSSITWDQLGEM 364

  Fly   370 KYLDMVVLEALRKWP--PSISTDRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHHDPENFED 432
            .|..|.:.|..|..|  ||||  |:..:.:...|  |..|   ..|..:.:.|:.|||:|..:::
Human   365 SYTTMCIKETCRLIPAVPSIS--RDLSKPLTFPD--GCTL---PAGITVVLSIWGLHHNPAVWKN 422

  Fly   433 PEFFNPERFADGHALESR--VYMPFGVGPRNCIGNRMALMELKSIVYQLLLNFKLLPAKRTSRDL 495
            |:.|:|.||:..::.:..  .|:||..|.|||||...|::|||..:..:||:|::.|........
Human   423 PKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTF 487

  Fly   496 LNDIRGHGLKPKNGFWL 512
            .|...   ||||||.:|
Human   488 PNHFI---LKPKNGMYL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	p450	38..512	CDD:278495	128/502 (25%)
CYP4X1	NP_828847.1	p450	47..501	CDD:306555	127/499 (25%)
		heme binding region	447..460		7/12 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900