Protein Alignment Cyp9h1 and Cyp3a18

DIOPT Version :10

• Sequence 1: NP_610820.1
• Gene: Cyp9h1 / 36412
• FlyBaseID: FBgn0033775
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_665725.2
• Gene: Cyp3a18 / 252931
• RGDID: 628709
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 496
• Identity: 141/496 - (28%)
• Similarity: 256/496 - (51%)
• Gaps: 41/496 - (8%)

  Fly     6 IALALFIIL---LVLLYKWSVAKYDVFSERGVSHEKPWPLIGNIPLKAMIGGMPVLKKMIELHTK 67
            :::..:::|   |:|.|.:....:.:|.:.|:...||.||.|.|    ...|..:.|...:.:.|
  Rat     7 LSIETWVLLATSLMLFYIYGTYSHGLFKKLGIPGPKPVPLFGTI----FNYGDGMWKFDDDCYKK 67

  Fly    68 HTGSPVYGIYALRDAVFFVRDPELIKLIGIKE-FDHFVNHNSMHNNIQESILSKSLISLRDGRWK 131
            :  ..::|.|........:.|||:||::.:|| :..|.|.....   ....:.|::....|..||
  Rat    68 Y--GKIWGFYEGPQPFLAIMDPEIIKMVLVKECYSVFTNRRCFG---PMGFMKKAITMSEDEEWK 127

  Fly   132 EMRNILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQLELSQDASIELEMKDYFTRFANDVIATVA 196
            .:|.||:|.||..|::.|:.|::...:.    :.:.|...:.....:.|||.|..::.|||...:
  Rat   128 RLRTILSPTFTSGKLKEMFPLMRQYGDT----LLKNLRREEAKGEPINMKDIFGAYSMDVITGTS 188

  Fly   197 FGISINSFRRKDNEFFRIGQAMSRISAWS--VVKAMLYALFPRLMKVLRIQVLDTKNIDYFSSLV 259
            ||::::|.....:.|.:..:.:.:...:.  ::..:|:.....:.::|...:...:::::|...|
  Rat   189 FGVNVDSLNNPQDPFVQKAKKILKFQIFDPFLLSVVLFPFLTPIYEMLNFSIFPRQSMNFFKKFV 253

  Fly   260 TAAMRYR-QEHKVVRPDMIHLLMEAKQQRLADLSDKSKDELYYSEFTADDLLAQCLLFFFAGFEI 323
            ....:.| ..::..|.|.:.|:|..:..: ...|.|:..:|        ::.||.::|.|.|::.
  Rat   254 KTMKKNRLDSNQKSRVDFLQLMMNTQNSK-GQESQKALSDL--------EMAAQAIIFIFGGYDA 309

  Fly   324 ISSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQ-PLTYDKLTKMKYLDMVVLEALRKWPPSI 387
            .|:|:.|:.:||...|.||.:|..||   ...|..: |:|||.|.:|:||||||.|:||.:|.:.
  Rat   310 TSTSISFIMYELATRPNVQKKLQNEI---DRALPNKAPVTYDALMEMEYLDMVVNESLRLYPIAT 371

  Fly   388 STDRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHHDPENFEDPEFFNPERFADGH--ALESR 450
            ..||..::|:::   ||..:   .||.|:.|||:.||.:||.:.:||.||||||:..:  :::..
  Rat   372 RLDRVSKKDVEI---NGVFI---PKGTVVTIPIYPLHRNPEYWLEPEEFNPERFSKENKGSIDPY 430

  Fly   451 VYMPFGVGPRNCIGNRMALMELKSIVYQLLLNFKLLPAKRT 491
            ||:|||.|||||||.|.||:.:|..|..:|.||.:.|.::|
  Rat   431 VYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFNIQPCEKT 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	CYP6-like	69..511	CDD:410679	126/430 (29%)
Cyp3a18	NP_665725.2	CYP3A	67..492	CDD:410743	127/432 (29%)