DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9h1 and cyp-25A6

DIOPT Version :9

Sequence 1:	NP_610820.1	Gene:	Cyp9h1 / 36412	FlyBaseID:	FBgn0033775	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001360017.1	Gene:	cyp-25A6 / 187059	WormBaseID:	WBGene00019438	Length:	235	Species:	Caenorhabditis elegans

Alignment Length:	216	Identity:	57/216 - (26%)
Similarity:	100/216 - (46%)	Gaps:	21/216 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MIALALFIILLVLLYKWSVAKYDVFSERGVSHEKPWPLIGN----IPLKAMIGGMPVLKKMIELH 65
            :::|..|||.::|..|   .::.:..:.|:|..:|..|:||    |..||.:|.........:||
Worm    10 LVSLVSFIIYVILARK---ERFRLRGKIGLSGPEPHWLMGNLKQIIERKAKLGYDDSYDWYNKLH 71

  Fly    66 TKHTGSPVYGIYALRDAVFFVRDPELIKLIGIKEFDHFVNHNS----MHNNIQESILSKSLISLR 126
             |..|. .:|||........:.:.|.||.:.||.|.:|.:...    ..|.::||:|..:.
Worm    72 -KQFGE-TFGIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIEDNKLKESLLQNTY---- 130

  Fly   127 DGRWKEMRNILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQLELSQDASIELEMKDYFTRFANDV 191
            :..||..|:.:.|.|:..||:.|::.|.|..:..:..::|:....|    :.::.|.|.....||
Worm   131 ESGWKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILKEKASSGQ----KWDIYDDFQGLTLDV 191

  Fly   192 IATVAFGISINSFRRKDNEFF 212
            |...||.|..|..|.:::.|:
Worm   192 IGKCAFAIDSNCQRDRNDIFY 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	p450	38..512	CDD:278495	49/183 (27%)
cyp-25A6	NP_001360017.1	p450	37..>215	CDD:386267	50/186 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166595
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.650