Protein Alignment Cyp9h1 and CYP4F8

DIOPT Version :9

• Sequence 1: NP_610820.1
• Gene: Cyp9h1 / 36412
• FlyBaseID: FBgn0033775
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_009184.1
• Gene: CYP4F8 / 11283
• HGNCID: 2648
• Length: 520
• Species: Homo sapiens
• Alignment Length: 586
• Identity: 132/586 - (22%)
• Similarity: 246/586 - (41%)
• Gaps: 158/586 - (26%)

  Fly     6 IALALFIILLVLLYKWSVAK-----YDVFSERG-------VSHEKPWPLIGNIPLKAMI-GGMPV 57
            :|.:.:::|||:...|.:|:     | .|...|       ...::.| .:|::.|.... .|:.|
Human    14 VAASPWLLLLVVGASWLLARILAWTY-AFYHNGRRLRCFPQPRKQNW-FLGHLGLVTPTEEGLRV 76

  Fly    58 LKKMIELHTKHTGSPVYGIYALRDAVFFVR------------DPELIKLIGIKEFDHFVNHNSMH 110
            |.:::..:.:.                |||            .|::::.:
Human    77 LTQLVATYPQG----------------FVRWLGPITPIINLCHPDIVRSV--------------- 110

  Fly   111 NNIQESILSKSLIS-------LRDG-------RWKEMRNILTPAFTGSKMRIMYDLIQSCSEE-G 160
            .|..::|..|.::.       |.||       :|:..|.:|||||   ...|:...|:..|:. .
Human   111 INTSDAITDKDIVFYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAF---HFNILKPYIKIFSKSAN 172

  Fly   161 VIHIQEQLELSQDASIELEMKDYFTRFANDVIATVAFGISINSFR-----------------RKD 208
            ::|.:.| .|:.:.|..|::.::.:....|.:....|....|...                 :::
Human   173 IMHAKWQ-RLAMEGSTCLDVFEHISLMTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRN 236

  Fly   209 NEFFRIGQAMSRISAWSVVKAMLYALFP---RLMKVLRI-------------QVLDTKNIDYFSS 257
            |:|||             .|..||.|.|   |..:..|:             :.|.::.:|.|
Human   237 NQFFR-------------YKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDF-- 286

  Fly   258 LVTAAMRYRQEHKVVRPDMIHLLMEAKQQRLADLSDKSKDELYYSEFTADDLLAQCLLFFFAGFE 322
                 ::.:.:.|.:  |.|.:|:.::.:...:|||             :|:.|:...|.|.|.:
Human   287 -----LQAKAKSKTL--DFIDVLLLSEDKNGKELSD-------------EDIRAEADTFMFGGHD 331

  Fly   323 IISSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQPLTYDKLTKMKYLDMVVLEALRKWPPSI 387
            ..:|.|.::.:.|..:|..|:|..:|:..:.::.:.:.:.:|.|.::.:|.|.:.|:||..||..
Human   332 TTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIP 396

  Fly   388 STDRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHHDPENFEDPEFFNPERFADGHALESR-- 450
            :..|.|.||:.|.|..     ...||:|..|.||::||:|..:.|||.::|.|| |....:.|
Human   397 TFARGCTQDVVLPDSR-----VIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRF-DPENAQKRSP 455

  Fly   451 -VYMPFGVGPRNCIGNRMALMELKSIVYQLLLNFKLLPAKRTSRDLLNDIRGHGLKPKNGFWLKF 514
             .::||..|||||||.:.|:.|:|.::...||.|::||..|..|.....:    |:.::|.||:.
Human   456 MAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHREPRRTPEIV----LRAEDGLWLRV 516

  Fly   515 E 515
            |
Human   517 E 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9h1	NP_610820.1	p450	38..512	CDD:278495	120/537 (22%)
CYP4F8	NP_009184.1	p450	52..504	CDD:306555	118/528 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810