DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sca and Mfap4

DIOPT Version :9

Sequence 1:	NP_476710.2	Gene:	sca / 36411	FlyBaseID:	FBgn0003326	Length:	799	Species:	Drosophila melanogaster
Sequence 2:	NP_001334474.1	Gene:	Mfap4 / 76293	MGIID:	1342276	Length:	281	Species:	Mus musculus

Alignment Length:	246	Identity:	83/246 - (33%)
Similarity:	118/246 - (47%)	Gaps:	54/246 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   539 PHDCSEVHT---QTDGLHLIAPAGQRHPLMTHC--TADG--WTTVQRRFDGSADFNRSWADYAQG 596
            |.||.:::.   |.||::||.|.|...|:...|  |.:|  ||..|:||:||..|.|.|:||..|
Mouse    40 PLDCDDIYAQGYQEDGVYLIYPYGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWSDYKLG 104

  Fly   597 FGAPGGEFWIGN------------------------EQLHHLTLDNCSRLQVQMQDIYDNVWVAE 637
            ||...||:|:|.                        :.||.|||.....|:|.::|..:|...|:
Mouse   105 FGRADGEYWLGKVGPWGGGCPSAKSLLTGCHPSLGLQNLHLLTLKQKYELRVDLEDFENNTAYAK 169

  Fly   638 YKRFYISSRA-----DGYRLHIAEY-SGNASDALNYQQGMQFSAIDDDRDISQTHCAANYEGGWW 696
            |..|.||..|     |||.|::|.: .|.|.|:|:|..|.:||..|.|:|:...:|||...|.:|
Mouse   170 YIDFSISPNAISAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFW 234

  Fly   697 FSHCQHANLNG--------RYNLGLTWFDAARNEW----IAVKSSRMLVKR 735
            |..|..|||||        .|..|:.|     .:|    .::|.:.|.::|
Mouse   235 FRSCHFANLNGFYLGGSHLSYANGINW-----AQWKGFYYSLKRTEMKIRR 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK13923	<200..300	CDD:276343
sca	NP_476710.2	FBG	538..736	CDD:214548	83/246 (34%)
Mfap4	NP_001334474.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H134529
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810