Protein Alignment sca and angptl2a

DIOPT Version :9

• Sequence 1: NP_476710.2
• Gene: sca / 36411
• FlyBaseID: FBgn0003326
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001025401.1
• Gene: angptl2a / 569092
• ZFINID: ZDB-GENE-080721-15
• Length: 525
• Species: Danio rerio
• Alignment Length: 567
• Identity: 132/567 - (23%)
• Similarity: 211/567 - (37%)
• Gaps: 168/567 - (29%)

  Fly   224 VQQRSSTFEDLATIRSDYQQLKLDLAAQRERQQQTEVYVQELREEMLQQEQDFQHALVKLQQRTR 288
            |.||.||  ....:.|...:..|:   .|..:|:.|:...||.::..|.|        .|||...
Zfish    70 VPQRKST--GAICVNSKEPEALLE---NRVNKQELELLNGELHKQRRQIE--------TLQQLVE 121

  Fly   289 KDGSSASVEEESGSQEANQEQTGLETTADHKRRHCRFQSEQIHQL--QLAQRNLRRQVNGLRFHH 351
            .||                   |:.......|:..|..:.::.||  ||....:|::.|.|....
Zfish   122 VDG-------------------GVVNEVKLLRKESRNMNARVTQLYMQLLHEIIRKRDNALEVSQ 167

  Fly   352 IDERVRSIEVEQHRIANANFNLSSQIASLDKLHTSMLELLEDVEGLQTKMDKSIPELRHEISKLE 416
            ::.||.:                         |||.::          ::.....:|.|:...|
Zfish   168 LENRVLN-------------------------HTSEMQ----------QLTSRYRDLEHKYQHL- 196

  Fly   417 FANAQITSEQSLIREEGTNAARSLQAMAVSVSVLQEEREGMRKLSANVDQLRTNVDRLQSLVNDE 481
               |.:.|.||                ||.|.:.::.|.|                   ..|...
Zfish   197 ---ASLASNQS----------------AVIVQLEEQCRRG-------------------GFVGGR 223

  Fly   482 MKNKLTHLNKPHKRPHHQNVQAQMPQDDSPIDSVLAET----------------LVSELENVETQ 530
            .       .:|::.|......||.||...|....:..:                :.:|::: :..
Zfish   224 Q-------TRPYQPPVVPPQPAQTPQHRQPPPPPVHHSPARPFHPPTYPRQNNQMTNEIQS-DQN 280

  Fly   531 YEAIINKLPHDCSEVHT-QTD--------------------GLHLIAPAGQRHPLMTHC----TA 570
            .:|:.:.||.:.||.|: .||                    |:.|:.|......:...|    ..
Zfish   281 SKAMPSALPTEQSETHSFSTDKLSGPFKDCLQALEEGHSNSGMFLLKPENTNKLMQVWCDQRHDP 345

  Fly   571 DGWTTVQRRFDGSADFNRSWADYAQGFGAPGGEFWIGNEQLHHLTLDNCSRLQVQMQDIYDNVWV 635
            .|||.:|||.|||.:|.|:|..|.||||...||:|:|.|.::.||.....:|.|.::|.......
Zfish   346 GGWTVIQRRMDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTLEDWSGRKTF 410

  Fly   636 AEYKRFYISSRADGYRLHIAEYSGNASDALNYQQGMQFSAIDDDRDISQTHCAANYEGGWWFSHC 700
            |||..|.:...||.|::.:..|.|||.|::.:..|.||:.:|.|.|....:||...:||||::.|
Zfish   411 AEYASFRLEPEADFYKMRVGRYHGNAGDSMTWHNGKQFTTLDRDHDAYTGNCAHYQKGGWWYNAC 475

  Fly   701 QHANLNG----------RYNLGLTWFDAARNEWIAVKSSRMLVKRLP 737
            .|:||||          ||..|:.|.: .|....::|...|:::..|
Zfish   476 AHSNLNGVWYRGGHYRSRYQDGVYWAE-FRGGSYSLKKVTMMIRPNP 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK13923	<200..300	CDD:276343	19/75 (25%)
		FBG	538..736	CDD:214548	75/232 (32%)
angptl2a	NP_001025401.1	DUF1875	<50..>147	CDD:286100	22/108 (20%)
		Fib_alpha	119..215	CDD:285864	27/169 (16%)
		FReD	305..519	CDD:238040	68/214 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900