DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sca and fgl1b

DIOPT Version :9

Sequence 1:	NP_476710.2	Gene:	sca / 36411	FlyBaseID:	FBgn0003326	Length:	799	Species:	Drosophila melanogaster
Sequence 2:	XP_017213536.1	Gene:	fgl1b / 563523	ZFINID:	ZDB-GENE-130530-668	Length:	348	Species:	Danio rerio

Alignment Length:	373	Identity:	105/373 - (28%)
Similarity:	157/373 - (42%)	Gaps:	83/373 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   429 IREEGTNAARSLQAMAVSVSVLQEEREGMRKLSANVDQLRTNVDRLQSLVNDEMKNKLTHLNKP- 492
            :.||||  :||:....|.:.:.    ..:..|.|:..      :..||....::|.::..||..
Zfish     4 LEEEGT--SRSVMPQLVFILIC----HALTLLQASAG------EECQSYEMSKLKEEIRMLNNKL 56

  Fly   493 --------HKRPHHQ-------NVQAQMPQDD----SP-IDSVLAETLVSELENVETQYEAIINK 537
                    |.|.|.:       .:|...|.::    || :.|.....||.:
Zfish    57 LIGEWKVMHLRTHRKFRLVPNLELQENKPSENNTEPSPTLPSTGGSLLVHD-------------- 107

  Fly   538 LPHDCSEVHTQ---TDGLHLIAPAGQRHPLMTHCTAD---GWTTVQRRFDGSADFNRSWADYAQG 596
              .||||::.:   ..|.:.|.|.....|.:.:|..|   .||.:|:|.:|..||:|.|.||..|
Zfish   108 --KDCSELYDRLKPVSGFYRIKPKPLLEPFLVYCDMDDGGAWTVIQKRINGKVDFDRKWEDYKNG 170

  Fly   597 FG---APGGEFWIGNEQLHHLTLDNCSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHIAEYS 658
            ||   :...|||:||:.:|.|..|..|.:::.:.|.......|.|..|.:|...|.|||:...||
Zfish   171 FGNFQSSKDEFWLGNDHIHVLLSDGDSVMKIDLTDWKGGKSYAMYDNFKVSDEKDKYRLYYGMYS 235

  Fly   659 GNASDALN-----------YQQGMQFSAIDDDRD-ISQTHCAANYEGGWWFSHCQHANLNGR--- 708
            |.|.|||:           ...|||||..|.|.| ..|..|||..:||||::.|..||||||
Zfish   236 GQAGDALSGGANMVEQWSASHNGMQFSTRDQDHDRYLQGSCAAENKGGWWYNRCHAANLNGRFYR 300

  Fly   709 -------YNLGLTWFDAARNEWIAVKSSRMLVKRLPAVECQANASASG 749
                   |:.|:.| ...:..|.:::.:.|.|:  |:....:..|..|
Zfish   301 GGEYKAKYDNGIVW-STWKGLWYSLRHTVMKVR--PSSHMDSVGSGGG 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK13923	<200..300	CDD:276343
sca	NP_476710.2	FBG	538..736	CDD:214548	78/228 (34%)
fgl1b	XP_017213536.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000