Protein Alignment sca and angptl6

DIOPT Version :10

• Sequence 1: NP_476710.2
• Gene: sca / 36411
• FlyBaseID: FBgn0003326
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001014821.1
• Gene: angptl6 / 561927
• ZFINID: ZDB-GENE-030131-9735
• Length: 489
• Species: Danio rerio
• Alignment Length: 533
• Identity: 141/533 - (26%)
• Similarity: 213/533 - (39%)
• Gaps: 149/533 - (27%)

  Fly   290 DGSSASVEEESGS---QEANQEQTGLETTADHKRRHCRFQSEQIHQLQLAQRNLRRQVNGLRFHH 351
            ||...||  .|||   .:|||::.  ...::.|:..|.:
Zfish    22 DGRKESV--GSGSSKGDDANQKRP--SRASETKQSRCSY-------------------------- 56

  Fly   352 IDERVRSIEVEQHRIANANFNLSSQIASLDKLHTSMLELLEDVEGLQTKMDKSIPELRHEISKLE 416
                  :..|.|.::..| ..|.::.|.:::...:.|..|  :|..|.::|:....|..|
Zfish    57 ------TFIVPQQKLTGA-LCLITESARVNRSEVASLRAL--LERQQDQLDQMRGRLEEE----- 107

  Fly   417 FANAQITSEQSLIREEGTNA-ARSLQAMAVSVSVL-------QEER--EG--------MRKLSAN 463
               ..:.||..::|.|..|. ||..|..|..:|.:       :|:|  ||        :.::|:|
Zfish   108 ---GTLASEMRILRRESVNMNARIAQLYAQLLSEIIQKKEQVEEQRRLEGLLLNATSQLHQVSSN 169

  Fly   464 VDQLRTNVDRLQSLVNDEMK-----------------------------NKLTHLN-------KP 492
            ...|....|.|.||||::.|                             :.|.::|       :.
Zfish   170 YRDLEKKYDTLASLVNNQSKIITLLEKQCQLKTSTKELQEATSLPAQQSSVLVNINTEPKDVQRD 234

  Fly   493 HKRPHHQNVQAQMPQ------DDSPIDSVLAETLVSELENVETQYEAI-INKLP---HDCSEV-- 545
            ...|.|   |||..|      ||||...            .||.:.:. ..|.|   |||..|
Zfish   235 QSAPFH---QAQARQELLETFDDSPGPP------------TETPFISFPSTKSPGPWHDCHNVLE 284

  Fly   546 -HTQTDGLHLIAPAGQRHPLMTHC----TADGWTTVQRRFDGSADFNRSWADYAQGFGAPGGEFW 605
             ..:|.|::|:.|......|...|    ...|||.:|||.|||.:|.|:|..|.||||...||:|
Zfish   285 SGEKTSGIYLLRPRNTNRLLQAWCDQSRAQGGWTVIQRRQDGSVNFFRTWDQYKQGFGNLDGEYW 349

  Fly   606 IGNEQLHHLTLDNCSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHIAEYSGNASDALNYQQG 670
            :|.|.|:.||.....:|:|.|:|.......|||..|.:...:|.|||.:..|.|.|.|:|::...
Zfish   350 LGLEHLYWLTSQATYKLRVAMEDWQGRQVYAEYDSFRVEPESDWYRLRLGSYQGTAGDSLSWHNN 414

  Fly   671 MQFSAIDDDRDISQTHCAANYEGGWWFSHCQHANLNG----------RYNLGLTWFDAARNEWIA 725
            ..|:.:|.|:|....:||...:||||:..|.|:||||          ||..|:.|.:.....: :
Zfish   415 KAFTTLDRDKDAYTGNCAHYQKGGWWYHMCAHSNLNGVWYRGGHYRSRYQDGVYWAEFHGGSY-S 478

  Fly   726 VKSSRMLVKRLPA 738
            :|...|::|  ||
Zfish   479 LKKVAMMIK--PA 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK03918	134..>485	CDD:235175	48/244 (20%)
		FBG	538..736	CDD:214548	76/217 (35%)
angptl6	NP_001014821.1	EnvC	63..>245	CDD:443969	41/195 (21%)
		FReD	274..488	CDD:238040	75/216 (35%)