DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sca and si:ch211-203k16.3

DIOPT Version :9

Sequence 1:	NP_476710.2	Gene:	sca / 36411	FlyBaseID:	FBgn0003326	Length:	799	Species:	Drosophila melanogaster
Sequence 2:	XP_021324371.1	Gene:	si:ch211-203k16.3 / 559151	ZFINID:	ZDB-GENE-041014-290	Length:	425	Species:	Danio rerio

Alignment Length:	418	Identity:	106/418 - (25%)
Similarity:	187/418 - (44%)	Gaps:	83/418 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   378 ASLDK--LHTSML----------ELLEDVEGLQTKMDKSIPELRHEISKLEFANAQITSEQSLIR 430
            ||.|:  |||..:          ::|||  |: .::..::|:|..:.....|   :.|.|.|...
Zfish    20 ASDDQHSLHTHQVSTAQCGEYSNQVLED--GM-CRLMATLPQLDEQRCPDMF---RCTDEVSYWL 78

  Fly   431 EEGTNAARSLQAMAVSVSVLQEE----REGMRKLSANVDQLRTNVDRLQSLVNDEMKNKLTHLNK 491
            .|.....:.:.|:..:||.||||    |..::.|....::...|...::..:: |::|   |..:
Zfish    79 HENEERKQQILALKETVSELQEELRNHRHRVKVLELQSEEKNHNSSSIEQRLH-ELEN---HYAE 139

  Fly   492 PHKRPHHQ-----NVQAQMPQDDSPIDSV------------------LAETLVSELENVETQYEA 533
            .....|.|     ::|||:......::.|                  ..|.|..|::||
Zfish   140 ASTLLHIQGSLIYDLQAQIHNLSMLVEKVRRNPGCMINIVRTSPLINAQEALHPEVQNV------ 198

  Fly   534 IINKLPHDCSEVH---TQTDGLHLIAPAGQRHPLMTHCTAD----GWTTVQRRFDGSADFNRSWA 591
              ...|.||:.::   .:..|::.:.|:....|:..:|..|    |||.:|||.|||.:|:|||.
Zfish   199 --RNCPIDCASIYYNGVRRSGIYTVVPSLGAMPVEVYCDMDTDGGGWTVIQRRQDGSVNFDRSWK 261

  Fly   592 DYAQGFGAPGGEFWIGNEQLHHLTLDNCSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHIAE 656
            :|.:|||....|:|:|||.:|.||......|::.::|..:....|.|:.|.:......||||::.
Zfish   262 EYKEGFGDLHTEYWLGNEHIHDLTSQGDYMLRIDLEDWSNKHKHALYQSFSVEDENTQYRLHVSG 326

  Fly   657 YSGNASDALNYQQGMQFSAIDDDRDISQTHCAANYEGGWWFSHCQHANLN------GRYNL---- 711
            :||...|:.::....|..:..|..:|    ||.....|||::.|.:.|||      |||:|
Zfish   327 FSGTVEDSFSWYHDKQGFSTPDTGNI----CAEISHAGWWYNQCFYTNLNGIYYKGGRYSLKGKN 387

  Fly   712 -----GLTWFDAARNEWIAVKSSRMLVK 734
                 |:.||....:::.:::...|:::
Zfish   388 SLGPDGVVWFTWKDSDYYSLRRVSMMIR 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK13923	<200..300	CDD:276343
sca	NP_476710.2	FBG	538..736	CDD:214548	65/219 (30%)
si:ch211-203k16.3	XP_021324371.1	SMC_N	73..>158	CDD:330553	20/88 (23%)
si:ch211-203k16.3	XP_021324371.1	FReD	202..417	CDD:238040	65/218 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910