Protein Alignment sca and Fga

DIOPT Version :9

• Sequence 1: NP_476710.2
• Gene: sca / 36411
• FlyBaseID: FBgn0003326
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001008724.1
• Gene: Fga / 361969
• RGDID: 2603
• Length: 782
• Species: Rattus norvegicus
• Alignment Length: 869
• Identity: 200/869 - (23%)
• Similarity: 323/869 - (37%)
• Gaps: 262/869 - (30%)

  Fly    37 LAVVLLQISVAFVSGAASGGVV--LSDVNNMLRDAKVVTSEKPVVHSKQETEAPESSVELLRFVD 99
            |.|..|.:|:|.....|..|..  ..:....:|..::|  |:.....| ||:.|        |..
  Rat     4 LRVACLILSLASTVWTADTGTTSEFIEAGGDIRGPRIV--ERQPSQCK-ETDWP--------FCS 57

  Fly   100 DDEDSEDISSIERQDGRTMESKKMADQVRLLTKQLNAL--MLRRREDYEMLEHNLRKSLRLT-TN 161
            |::.:....|..|..|...|:.:  |....:.|..|:|  ..:..:|...|..|:.:.||.. .|
  Rat    58 DEDWNHKCPSGCRMKGLIDEANQ--DFTNRINKLKNSLFDFQKNNKDSNSLTRNIMEYLRGDFAN 120

  Fly   162 ANSVDADMRSELNQLREELAALRSSQSGNKERLTVEWLQQ---TISEIRKQLVDLQRTASNVAQD 223
            ||:.|.........||..:..|:        |..:|..||   ...::|.||:|::|...::  |
  Rat   121 ANNFDNTFGQVSEDLRRRIEILK--------RKVIEKAQQIQVLQKDVRDQLIDMKRLEVDI--D 175

  Fly   224 VQQRSSTFEDLATIR-----SDY--QQLKL------DLAAQRERQQQTEVYVQELRE-------E 268
            ::.||.......::.     .||  ||.:|      :|...::||....:.:..:.:       .
  Rat   176 IKIRSCKGSCSRSVSREINLKDYEGQQKQLEQVIAKELLPAKDRQYLPAIKMSPVPDLVPGSFKS 240

  Fly   269 MLQQEQDFQHALVKLQQ------RTRKDGSS------------------ASVEE----------- 298
            .||:......||.:::|      |..|||:|                  :.:|.
  Rat   241 QLQEGPPEWKALTEMRQMRMELERPGKDGASRGDLPGDSRGDSATRGPGSKIENPMTPGHGGSGY 305

  Fly   299 ----ESGS-QEAN--QEQTGLETTADHKRRHCRFQSEQIHQLQLAQRNLRRQVNGLRFHHIDERV 356
                .||| .:.|  ...||.:.|........|..|        ...||:.
  Rat   306 WRPGSSGSGSDGNWGSGTTGSDDTGTWGAGSSRPSS--------GSGNLKP-------------- 348

  Fly   357 RSIEVEQHRIAN------ANFNLSSQIASLDKLHTSMLELLEDVEGLQTKMDKSIPELRHEISKL 415
                      :|      :.|..||..|:..:.||..|        :.:|.||          :|
  Rat   349 ----------SNPDWGEFSEFGGSSSPATRKEYHTGKL--------VTSKGDK----------EL 385

  Fly   416 EFANAQITSEQSLIREEGTNAARSLQAMAVSVSVLQEE--REGMRKL------------------ 460
            ...|.::||       .||:..|...:..::.:||..:  ||.::::
  Rat   386 LIGNEKVTS-------TGTSTTRRSCSKTITKTVLGNDGHREVVKEVVTSDDGSDCGDGMDLGLT 443

  Fly   461 ---SANVDQ------------------LRTNVDRLQSLVND-----EMKNKLTHLNKPHKRPHHQ 499
               |..:|:                  |.:|.....|..:|     :::|..:|:.:........
  Rat   444 HSFSGRLDELSRMHPELGSFYDSRFGSLTSNFKEFGSKTSDSDIFTDIENPSSHVPEFSSSSKTS 508

  Fly   500 NVQAQMPQDDSPIDSVLAE------TLVSELENVETQYEAIINKLPHDCSEVHTQT------DGL 552
            .|:.|:.:.....|...:|      |..::.....|.         .||.:| .||      :|:
  Rat   509 TVRKQVTKSYKMADEAASEAHQEGDTRTTKRGRARTM---------RDCDDV-LQTHPSGAQNGI 563

  Fly   553 HLIAPAGQRHPLMTHCTAD----GWTTVQRRFDGSADFNRSWADYAQGFGAPG----GEFWIGNE 609
            ..|...|.......:|..:    ||..:|:|.|||.:|||:|.||.:|||:..    ||||:||:
  Rat   564 FSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGND 628

  Fly   610 QLHHLTLDNCSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHIAEYSGNASDAL---NYQQG- 670
            .||.|||.. |.|:|:::|.......||| .|.:.|.|:||.|.::.|.|.|.|||   :.::|
  Rat   629 YLHLLTLRG-SVLRVELEDWAGKEAYAEY-HFRVGSEAEGYALQVSSYQGTAGDALMEGSVEEGT 691

  Fly   671 -------MQFSAIDDDRDISQTHCAANYEGGWWFSHCQHANLNGRYNLGLTWFDAARNE------ 722
                   ||||..|.|.|..:.:||..|.||||::.||.|||||.|..|.| :|...|.
  Rat   692 EYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGT-YDPRNNSPYEIEN 755

  Fly   723 ---WI-------AVKSSRMLVKRL 736
               |:       ::::.||.::.|
  Rat   756 GVVWVPFRGADYSLRAVRMKIRPL 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK13923	<200..300	CDD:276343	29/161 (18%)
		FBG	538..736	CDD:214548	85/238 (36%)
Fga	NP_001008724.1	Fib_alpha	51..189	CDD:285864	36/157 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..374		23/141 (16%)
		Fibrinogen_aC	388..453	CDD:288972	12/71 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..542		3/19 (16%)
		FReD	546..779	CDD:238040	85/236 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900