DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sca and Fibcd1

DIOPT Version :9

Sequence 1:	NP_476710.2	Gene:	sca / 36411	FlyBaseID:	FBgn0003326	Length:	799	Species:	Drosophila melanogaster
Sequence 2:	NP_001101299.1	Gene:	Fibcd1 / 311861	RGDID:	1309097	Length:	459	Species:	Rattus norvegicus

Alignment Length:	423	Identity:	120/423 - (28%)
Similarity:	181/423 - (42%)	Gaps:	93/423 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 ANANFNLSSQIASLDKLHTSMLELLEDVEGLQTKMDKSIPELRHEISKLEFANAQI----TSEQS 427
            |.||    |.:.::::..:|.|.||         :|...|:|....::||...|.|    :..|:
  Rat    73 AGAN----SALVTVERADSSHLSLL---------IDPRCPDLTDSFARLEGIQASILRTLSEHQA 124

  Fly   428 LIREEGTNAARSLQAMA-------VSVSVLQEEREGMRK----LSANVDQLRTNVDRLQSLVNDE 481
            ..|.:|  |...|.|:|       ...|.||.|..|:||    |...:..|::...||..|:: |
  Rat   125 QPRLDG--APELLDALADQLPRLLARASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLS-E 186

  Fly   482 MKNKLTHLNKPHKRPHHQNVQAQMPQDDSPIDSV--LAETLVSELENVETQYEAIINKL------ 538
            .:..:.||                      ::||  :.|.|..|......:.:|.:.:.
  Rat   187 SQGHMAHL----------------------VNSVSDVLEALQRERGLGRPRVKADLQRAPSRGAR 229

  Fly   539 ---------PHDCSEV---HTQTDGLHLIAPAGQRHPLMTHC----TADGWTTVQRRFDGSADFN 587
                     |.||.:|   ..|.||::.:.|.........:|    ...|||..|||.|||.:|.
  Rat   230 PRGCANGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFF 294

  Fly   588 RSWADYAQGFGAPGGEFWIGNEQLHHLTLDNCSRLQVQMQDIYDNVWVAEYKR-----FYISSRA 647
            |.|..|.:|||...||.|:|.:::|.||......|.|.::|..:....|.|..     |.:....
  Rat   295 RGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEE 359

  Fly   648 DGYRLHIAEYSGNASDALNYQQGMQFSAIDDDRDISQTHCAANYEGGWWFSHCQHANLNGRYNLG 712
            |||.|.:|:|||.|.|:|....||:|:..|.|.|.|:.:|||.|.|.||:.:|..:||||:|..|
  Rat   360 DGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRG 424

  Fly   713 --LTWFDAARNEW-------IAVKSSRMLVKRL 736
              .::.|..  ||       .::|.|.|.::.|
  Rat   425 PHASYADGV--EWSSWTGWQYSLKFSEMKIRPL 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK13923	<200..300	CDD:276343
sca	NP_476710.2	FBG	538..736	CDD:214548	76/233 (33%)
Fibcd1	NP_001101299.1	FReD	239..455	CDD:238040	76/217 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810