Protein Alignment sca and Angpt4

DIOPT Version :10

• Sequence 1: NP_476710.2
• Gene: sca / 36411
• FlyBaseID: FBgn0003326
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001099996.1
• Gene: Angpt4 / 296269
• RGDID: 1307539
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 590
• Identity: 138/590 - (23%)
• Similarity: 232/590 - (39%)
• Gaps: 127/590 - (21%)

  Fly   180 LAALRSSQ------SGNKERLTVEWLQQTISEIRKQLVDLQRTASNVAQDVQQRSSTFEDLATIR 238
            ||.:.::|      ||.::...|:..|.:.:.:..: .|:.:.|....:.:...:|...||...|
  Rat    15 LATMAAAQHRGPEASGRRQIHRVQHGQCSYTFVLPE-PDICQLAPVAPEGLGGSNSLQRDLPAAR 78

  Fly   239 SDYQQLKLDLAAQRERQQQTEVYVQELREEMLQQEQDFQ----HALVKLQQRTRKDGSSASVEEE 299
            ......:...|.:.:|..|.|..::...:.:|:.||..|    ..|.:.||.|.::.::..:...
  Rat    79 HHLTDWRAQRAQRAQRVSQLEKILENNTQWLLKLEQSIQMNLRSDLAQAQQHTIQNQTTTMLALG 143

  Fly   300 SGSQEANQEQTGLETTADHK-RRHCRFQSEQIHQLQLAQRNLRRQVNGLRFHHIDERVRSIEVEQ 363
            :........||...|..:.: ..|......|:.:..|:...|.||:          .::|.|::
  Rat   144 ANLMNQTMAQTHKLTAVEAQVLNHTSRVKTQMLESSLSTNKLERQM----------LMQSRELQ- 197

  Fly   364 HRIANANFNLSSQIASLDKLHTSMLELLEDV-EGLQTKMDKSIPELRHEISKLEFANAQITSEQS 427
             |:...|..|.:::.:|:..|.:.|..|:|. |.||:.       |.|:...|
  Rat   198 -RLQGRNRALETRLQALEAQHQAQLNSLQDKREQLQSL-------LGHQTGAL------------ 242

  Fly   428 LIREEGTNAARSLQAMAVSVSVLQEEREGMRKLSANVDQLRTNVDRLQSLVNDEMKNKLTHLNKP 492
                  .|...||:|::.:.|.||::::          ||...|.||..:|
  Rat   243 ------ANLKHSLRALSSNSSSLQQQQQ----------QLMELVQRLVRIV-------------- 277

  Fly   493 HKRPHHQNVQAQMPQDDSPIDSVLAETLVSELENVETQYEAIINKLPHDCSEVH---TQTDGLHL 554
                         .||..|:.....:.|.                  .||:|:.   ..|.|::.
  Rat   278 -------------AQDQHPVSLKTPKPLF------------------RDCAEIKRSGANTSGVYT 311

  Fly   555 IAPAGQRHPLMTHCTAD----GWTTVQRRFDGSADFNRSWADYAQGFGAPGGEFWIGNEQLHHLT 615
            |..|....||...|..:    |||.:|||.|||.:|.|:|.:|.:|||....|.|:|||.:|.||
  Rat   312 IHGANMTKPLKVFCDMETDGGGWTLIQRREDGSLNFQRTWEEYKEGFGNVAREHWLGNEAVHSLT 376

  Fly   616 LDNCSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHI--AEYSGNASDALNYQQGMQFSAIDD 678
            ......|:|::.|...:....:|:.|.:.|....|.|.:  :..|....::| ..||.:||..|.
  Rat   377 SRTAYLLRVELHDWEGHQTSIQYENFQLGSERQRYSLSVNDSSISARLKNSL-APQGTKFSTKDM 440

  Fly   679 DRDISQTHCAANYEGGWWFSHCQHANLNGRY----------NLGLTWFDAARNEWIAVKSSRMLV 733
            |.|.....||....|||||..|..:||||.|          | |:.| ...|....::..:||::
  Rat   441 DNDNCMCKCAQMLSGGWWFDACGLSNLNGIYYPVHQHLHKIN-GIRW-HYFRGPSYSLHGTRMML 503

  Fly   734 KRLPA 738
            :.:.|
  Rat   504 RPMGA 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK03918	134..>485	CDD:235175	63/316 (20%)
		FBG	538..736	CDD:214548	70/216 (32%)
Angpt4	NP_001099996.1	SMC_N	98..>233	CDD:481474	30/146 (21%)
		FReD	291..506	CDD:238040	71/235 (30%)