DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sca and Fgl1

DIOPT Version :9

Sequence 1:	NP_476710.2	Gene:	sca / 36411	FlyBaseID:	FBgn0003326	Length:	799	Species:	Drosophila melanogaster
Sequence 2:	NP_742007.2	Gene:	Fgl1 / 246186	RGDID:	620169	Length:	314	Species:	Rattus norvegicus

Alignment Length:	317	Identity:	96/317 - (30%)
Similarity:	139/317 - (43%)	Gaps:	72/317 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   450 LQEEREGMRKLSANVDQLRTNVDRLQSLVNDEMKNKLTHLNKPHKRPHHQNVQ-AQMPQDDSPID 513
            |||:    .:|.|.|.||.|.|.:.|.::...:              |.:.|| ....|:||.||
  Rat    29 LQEQ----VRLRAQVRQLETRVKQQQVVIAQLL--------------HEKEVQFLDRGQEDSFID 75

  Fly   514 SVLAETLVSELENVETQYEAIINKLPH--DCSEVHT---QTDGLHLIAPAGQRHPLMTHC---TA 570
                                 :....|  ||||::.   :..|.:.|.|.........:|   ..
  Rat    76 ---------------------LGGKRHYADCSEIYNDGFKHSGFYKIKPLQSLAEFSVYCDMSDG 119

  Fly   571 DGWTTVQRRFDGSADFNRSWADYAQGFG---APGGEFWIGNEQLHHLTLDNCSRLQVQMQDIYDN 632
            .|||.:|||.|||.:|||.|.||..|||   ...||:|:||:.::.||:.....|::.:.|...|
  Rat   120 GGWTVIQRRSDGSENFNRGWNDYENGFGNFVQSNGEYWLGNKNINLLTMQGDYTLKIDLTDFEKN 184

  Fly   633 VWVAEYKRFYISSRADGYRLHIAEYSGNASDALN-----------YQQGMQFSAIDDDRDISQTH 686
            ...|:|::|.:......|.|:|.||||.|.|:|:           ..|.|:||..|.|.|....:
  Rat   185 SRFAQYEKFKVGDEKSFYELNIGEYSGTAGDSLSGTFHPEVQWWASHQTMKFSTRDRDNDNYNGN 249

  Fly   687 CAANYEGGWWFSHCQHANLNGRY---------NLGLTWFDAARNEWIAVKSSRMLVK 734
            ||...:.||||:.|..|||||.|         :.|:.|: ..|..|.::||..|.::
  Rat   250 CAEEEQSGWWFNRCHSANLNGVYYQGPYRAETDNGVVWY-TWRGWWYSLKSVVMKIR 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK13923	<200..300	CDD:276343
sca	NP_476710.2	FBG	538..736	CDD:214548	77/228 (34%)
Fgl1	NP_742007.2	FReD	80..306	CDD:238040	77/227 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100