DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sca and Fgg

DIOPT Version :9

Sequence 1:	NP_476710.2	Gene:	sca / 36411	FlyBaseID:	FBgn0003326	Length:	799	Species:	Drosophila melanogaster
Sequence 2:	XP_006232587.1	Gene:	Fgg / 24367	RGDID:	2613	Length:	445	Species:	Rattus norvegicus

Alignment Length:	417	Identity:	101/417 - (24%)
Similarity:	168/417 - (40%)	Gaps:	99/417 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   398 QTKMDKSIPELRHEISKLEFANAQITSEQSLIREEGTNAARSLQAMAVSVSVLQEEREGM----- 457
            ||.:|..:..|.:.:.:.|              ...|.|...::|:.|..:..|..:.||
  Rat    59 QTDVDTDLQTLENILQRAE--------------NRTTEAKELIKAIQVYYNPDQPPKPGMIEGAT 109

  Fly   458 RKLSANVDQL----------RTNVDRLQSLVNDEMKNKLTHLNKPHKRPHHQNVQAQMPQDDSPI 512
            :|....|:::          .:::..||.:.... |.|:|:|.   ::......|.|.|..||
  Rat   110 QKSKKMVEEILKYEALLLTHESSIRYLQDIYTSN-KQKITNLK---QKVAQLEAQCQEPCKDS-- 168

  Fly   513 DSVLAETLVSELENVETQYEAIINKLPHDCSEV---HTQTDGLHLIAPAGQRHPLMTHCTAD--- 571
                               ..|.:....||.::   ..:..||:.|.|.......:.:|..|
  Rat   169 -------------------VRIHDTTGKDCQDIANKGAKESGLYFIRPLKATQQFLVYCEIDGSG 214

  Fly   572 -GWTTVQRRFDGSADFNRSWADYAQGFG--APGG--EFWIGNEQLHHLTLDNC--SRLQVQMQDI 629
             |||.:|:|.|||.||.::|..|.:|||  :|.|  |||:|||::|.:::.:.  ..|::|::|.
  Rat   215 NGWTVLQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISMQSTIPYALRIQLKDW 279

  Fly   630 YDNVWVAEYKRFYISSRADGYRLHIAEY-SGNASDALN--------------YQQGMQFSAIDDD 679
            ......|:|..|.:...:|.|||..|.: .|:|.||.:              ...||.||..|:|
  Rat   280 SGRTSTADYAMFRVGPESDKYRLTYAYFIGGDAGDAFDGYDFGDDPSDKFFTSHNGMHFSTWDND 344

  Fly   680 RDISQTHCAANYEGGWWFSHCQHANLNGRYNLGLTWFDAA--------------RNEWIAVKSSR 730
            .|..:.:||.....|||.:.|...:|||.|..|.|:..::              :..|.::|.:.
  Rat   345 NDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKSSTPNGYDNGIIWATWKTRWYSMKETT 409

  Fly   731 MLV---KRLPAVECQANASASGAFVSV 754
            |.:   .||...:.|.:.......|||
  Rat   410 MKIIPFNRLSIGDGQQHHMGGSKQVSV 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK13923	<200..300	CDD:276343
sca	NP_476710.2	FBG	538..736	CDD:214548	69/242 (29%)
Fgg	XP_006232587.1	Fib_alpha	31..172	CDD:400857	25/151 (17%)
Fgg	XP_006232587.1	Fibrinogen_C	175..414	CDD:395095	69/238 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900