Protein Alignment sca and Angptl2

DIOPT Version :10

• Sequence 1: NP_476710.2
• Gene: sca / 36411
• FlyBaseID: FBgn0003326
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_598253.2
• Gene: Angptl2 / 171100
• RGDID: 620004
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 441
• Identity: 120/441 - (27%)
• Similarity: 191/441 - (43%)
• Gaps: 75/441 - (17%)

  Fly   361 VEQHRIANA---NFNLSSQIASLDKLHTSMLELLEDVEGLQTKMDKSIPELRHEISKLEFANAQI 422
            |.|.|:..|   | :...::...:::|...||||.: |.|:.|  :.|..|:    :|...:..|
  Rat    60 VPQQRVTGAICVN-SKEPEVHLENRVHKQELELLNN-ELLKQK--RQIETLQ----QLVEVDGGI 116

  Fly   423 TSEQSLIREEGTNA-ARSLQAMAVSVSVLQEEREGMRKLSANVDQ-LRTNVDRLQ--SLVNDEMK 483
            .||..|:|:|..|. :|..|.....:..:..:|:...:||...:: |....|.||  |...| ::
  Rat   117 VSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKD-LE 180

  Fly   484 NKLTHLNK-PHKR--------PHHQNVQAQMPQDDSP-------IDSVLAETLVSELENVETQYE 532
            :|..||.. .|.:        .|.|.|.|..|....|       ........:::::...|.|.:
  Rat   181 HKFQHLAMLAHNQSEVIAQLEEHCQRVPAARPVPQPPPATPPRVYQPPTYNRIINQISTNEIQSD 245

  Fly   533 AIINKLP-----------------------HDCSEV----HTQTDGLHLIAPAGQRHPLMTHC-- 568
            ..:..||                       .||.:.    |: |..::|:.|......:...|
  Rat   246 QNLKVLPPSLPTMPALTSLPSSTDKPSGPWRDCLQALEDGHS-TSSIYLVKPENTNRLMQVWCDQ 309

  Fly   569 --TADGWTTVQRRFDGSADFNRSWADYAQGFGAPGGEFWIGNEQLHHLTLDNCSRLQVQMQDIYD 631
              ...|||.:|||.|||.:|.|:|..|.||||...||:|:|.|.::.||.....:|.|.|:|...
  Rat   310 RHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSG 374

  Fly   632 NVWVAEYKRFYISSRADGYRLHIAEYSGNASDALNYQQGMQFSAIDDDRDISQTHCAANYEGGWW 696
            ....|||..|.:...::.|:|.:..|.|||.|:..:..|.||:.:|.|.|:...:||...:||||
  Rat   375 RKVFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWW 439

  Fly   697 FSHCQHANLNG----------RYNLGLTWFDAARNEWIAVKSSRMLVKRLP 737
            ::.|.|:||||          ||..|:.|.: .|....::|...|:::..|
  Rat   440 YNACAHSNLNGVWYRGGHYRSRYQDGVYWAE-FRGGSYSLKKVVMMIRPNP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK03918	134..>485	CDD:235175	34/130 (26%)
		FBG	538..736	CDD:214548	73/238 (31%)
Angptl2	NP_598253.2	t_SNARE	156..>206	CDD:197699	12/50 (24%)
		FReD	273..487	CDD:238040	71/215 (33%)