Protein Alignment sca and Fga

DIOPT Version :10

• Sequence 1: NP_476710.2
• Gene: sca / 36411
• FlyBaseID: FBgn0003326
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001104518.1
• Gene: Fga / 14161
• MGIID: 1316726
• Length: 789
• Species: Mus musculus
• Alignment Length: 863
• Identity: 218/863 - (25%)
• Similarity: 324/863 - (37%)
• Gaps: 243/863 - (28%)

  Fly    37 LAVVLLQISVA---FVSGAASGGVVLSDVNNMLRDAKVVTSEKPVVHSKQ--ETEAPESSVELLR 96
            |.|..|.:|||   :.:.....|..||: ...:|..:||..     |..|  :::.|
Mouse     4 LRVTCLILSVASTVWTTDTEDKGEFLSE-GGGVRGPRVVER-----HQSQCKDSDWP-------- 54

  Fly    97 FVDDDEDSEDISSIERQDGRTMESKKMADQVRLLTKQLNAL--MLRRREDYEMLEHNLRKSLRLT 159
            |..||:.:....|..|..|...|:.:  |....:.|..|:|  ..|..:|...|..|:.:.||..
Mouse    55 FCSDDDWNHKCPSGCRMKGLIDEANQ--DFTNRINKLKNSLFDFQRNNKDSNSLTRNIMEYLRGD 117

  Fly   160 -TNANSVDADMRSELNQLREELAALRSSQSGNKERLTVEWLQQ---TISEIRKQLVDLQRTASNV 220
             .|||:.|.........||..:..||        |..:|..||   ..|.:|.||:|::|...::
Mouse   118 FANANNFDNTYGQVSEDLRRRIEILR--------RKVIEKAQQIQALQSNVRAQLIDMKRLEVDI 174

  Fly   221 AQDVQQRSS------------TFEDLATIRSDYQQ-LKLDLAAQRERQQQTEVYVQELR------ 266
              |::.||.            ..:|....:...|| :..:|...::||     |:..|:
Mouse   175 --DIKIRSCKGSCSRAVNREINLQDYEGHQKQLQQVIAKELLPTKDRQ-----YLPALKMSPVPD 232

  Fly   267 ------EEMLQQEQDFQHALVKLQQ------RTRKDGSS---------------------ASVEE 298
                  :..||:......||.:::|      |..|||.|                     .|..|
Mouse   233 LVPGSFKSQLQEAPPEWKALTEMRQMRMELERPGKDGGSRGDSPGDSRGDSRGDFATRGPGSKAE 297

  Fly   299 E------------------SGSQ-EANQEQTGLETTADHKRRHCRFQSEQIHQLQLAQRNLRRQV 344
            .                  |||. ..|...||.:.|.|......|..|:.
Mouse   298 NPTNPGPGGSGYWRPGNSGSGSDGNRNPGTTGSDGTGDWGTGSPRPGSDS--------------- 347

  Fly   345 NGLRFHHIDERVRSIEVEQHRIANAN------FNLSSQIASLDKLHTSML-------ELLEDVE- 395
                             ...|.||.|      |..||..|:..:.||...       |||...|
Mouse   348 -----------------GNFRPANPNWGVFSEFGDSSSPATRKEYHTGKAVTSKGDKELLIGKEK 395

  Fly   396 ----GLQT---KMDKSI------PELRHEISKLEFANAQITSEQSLIREEGTNAARSLQAMAVSV 447
                |..|   ...|:|      |:.|.|:.|     ..|||      ::|::...:.: :.:|.
Mouse   396 VTSSGTSTTHRSCSKTITKTVTGPDGRREVVK-----EVITS------DDGSDCGDATE-LDISH 448

  Fly   448 SV---LQEEREGMRKLSANVDQ----LRTNVDRLQSLVNDEMKNKLTHLNKPHKR-PHHQN---- 500
            |.   |.|..|....||...|.    :..|.....|..:.: .:.||::..|... |...:
Mouse   449 SFSGSLDELSERHPDLSGFFDNHFGLISPNFKEFGSKTHSD-SDILTNIEDPSSHVPEFSSSSKT 512

  Fly   501 --VQAQMPQDDSPIDSVLAETLVSELENVETQYEAIINKLPHDCSEV-HTQT----DGLHLIAPA 558
              |:.|:.:.....|...:|. ..|.|...|:......:...||.:| .|||    :|:..|.|.
Mouse   513 STVKKQVTKTYKMADEAGSEA-HREGETRNTKRGRARARPTRDCDDVLQTQTSGAQNGIFSIKPP 576

  Fly   559 GQRHPLMTHCTAD----GWTTVQRRFDGSADFNRSWADYAQGFGAPG----GEFWIGNEQLHHLT 615
            |.......:|..:    ||..:|:|.|||.:|||:|.||.:|||:..    ||||:||:.||.||
Mouse   577 GSSKVFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLT 641

  Fly   616 LDNCSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHIAEYSGNASDAL---NYQQG------- 670
            |.. |.|:|:::|.......||| .|.:.|.|:||.|.::.|.|.|.|||   :.::|
Mouse   642 LRG-SVLRVELEDWAGKEAYAEY-HFRVGSEAEGYALQVSSYRGTAGDALVQGSVEEGTEYTSHS 704

  Fly   671 -MQFSAIDDDRDISQTHCAANYEGGWWFSHCQHANLNGRYNLGLTWFDAARNE---------WI- 724
             ||||..|.|.|..:.:||..|.||||::.||.|||||.|..|.| :|...|.         |:
Mouse   705 NMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGT-YDPRNNSPYEIENGVVWVP 768

  Fly   725 ------AVKSSRMLVKRL 736
                  ::::.||.::.|
Mouse   769 FRGADYSLRAVRMKIRPL 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK03918	134..>485	CDD:235175	95/461 (21%)
		FBG	538..736	CDD:214548	87/237 (37%)
Fga	NP_001104518.1	Fib_alpha	50..192	CDD:462570	39/161 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	263..420		35/188 (19%)
		dermokine	<265..>401	CDD:455732	30/167 (18%)
		Fibrinogen_aC	392..457	CDD:432370	16/76 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..555		5/29 (17%)
		FReD	550..786	CDD:238040	87/238 (37%)