Protein Alignment sca and angpt1

DIOPT Version :10

• Sequence 1: NP_476710.2
• Gene: sca / 36411
• FlyBaseID: FBgn0003326
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_571888.1
• Gene: angpt1 / 114407
• ZFINID: ZDB-GENE-010817-1
• Length: 513
• Species: Danio rerio
• Alignment Length: 512
• Identity: 117/512 - (22%)
• Similarity: 221/512 - (43%)
• Gaps: 112/512 - (21%)

  Fly   227 RSSTFEDLATIRSDYQQLKLDLAAQRERQQQTEVYVQELREEMLQQEQDF-----QHALVKLQQR 286
            :|.|..:...::.|..|.:.||:.|:.:|.:   :|.|...:.||:.:::     :..:|:|||.
Zfish    68 KSGTAYNANALQRDAPQPEADLSNQKIQQLE---HVMENYTQWLQKIENYIKDNMKTEMVQLQQS 129

  Fly   287 TRKDGSSASVEEESGSQEANQEQTGLETTADHKRRHCRFQSEQIHQLQLAQRNLRRQVNGLRFHH 351
            ...:.::|.:  |.|:...:|                  .:||..:|...:..:..|.:.|....
Zfish   130 AVHNHTAAML--EMGTSLLSQ------------------TAEQTRKLTDVETQVLNQTSRLEIQL 174

  Fly   352 IDERVRSIEVEQHRIANANFNLSSQIASLDKLHTSMLELLEDVEGLQTKMDKSIPELRHEISKLE 416
            ::..:.:.::|:        .|..||..::|:|.....|.|.::.|:.:..:.:..||.|.|.|:
Zfish   175 LENSLSTNKLEK--------QLMIQINEINKIHDKNGFLEEKMQELEDRHRQELESLRTEKSDLQ 231

  Fly   417 FANAQITSEQSLIREEGTNAARSLQAMAVSVSVLQEEREGMRKLSANVDQLRTNVDRLQSLVNDE 481
               |.::.:.|:|||.....:|:    ..:.:.||.:::.:             ::.::||:
Zfish   232 ---ALVSRQSSVIRELENQLSRA----TGNSTALQRQQQDL-------------MESMRSLL--- 273

  Fly   482 MKNKLTHLNKPHKRPHHQNVQAQMPQDDSPIDSVLAETLVSELENVETQYEAIINKLPHDCSEVH 546
                                            |:.|:...:.:|...|: :|...:...||::::
Zfish   274 --------------------------------SLCAKDAATAVEPNSTK-QADEERKFRDCADLY 305

  Fly   547 T---QTDGLHLIAPAGQRHPLMTHCTAD----GWTTVQRRFDGSADFNRSWADYAQGFGAPGGEF 604
            .   |.:|::.|..:.| .....:|..:    |||.:|:|.||:.||.::|.:|..|||:..||.
Zfish   306 QAGFQKNGVYTINISPQ-ETKKVYCVMESAGGGWTVIQKREDGTVDFQKTWKEYKMGFGSVSGEH 369

  Fly   605 WIGNEQLHHLTLDNCSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHIAEYSGNASDALNYQ- 668
            |:|||.:|.||......|:|::.|...:...::|..|:|.|....|||.:..:||.|....:..
Zfish   370 WLGNEFVHVLTNQRQHGLRVELSDWDGHQAFSQYDSFHIDSEKQKYRLFLKTHSGTAGRQSSLAV 434

  Fly   669 QGMQFSAIDDDRDISQTHCAANYEGGWWFSHCQHANLN----------GRYNLGLTW 715
            .|..||..|.|.|.....||....||||:..|..:|||          |::| |:.|
Zfish   435 HGADFSTKDVDNDNCTCKCALMLSGGWWYDACGPSNLNGVYYRQGQHVGKFN-GIKW 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK03918	134..>485	CDD:235175	49/262 (19%)
		FBG	538..736	CDD:214548	63/196 (32%)
angpt1	NP_571888.1	SMC_N	<77..289	CDD:481474	50/297 (17%)
		FReD	298..508	CDD:238040	63/195 (32%)