Protein Alignment sca and angpt2a

DIOPT Version :10

• Sequence 1: NP_476710.2
• Gene: sca / 36411
• FlyBaseID: FBgn0003326
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001265754.1
• Gene: angpt2a / 101101687
• ZFINID: ZDB-GENE-121101-1
• Length: 488
• Species: Danio rerio
• Alignment Length: 525
• Identity: 119/525 - (22%)
• Similarity: 215/525 - (40%)
• Gaps: 139/525 - (26%)

  Fly   242 QQLKLDLAAQRERQQQTEVYVQE-LREEMLQ-QEQDFQHALVKLQQRTRKDGSSASVEEESGSQE 304
            :||:..:....:..|:.|.|::| |:::|:| |....|:..|.:    .|.|:|.
Zfish    73 EQLESIIENNTQWLQKLENYIEENLKQDMVQIQNNAVQNHTVTM----IKIGTSL---------- 123

  Fly   305 ANQEQTGLETTADHKRRHCRFQSEQIHQLQLAQRNLRRQVNGLRFHHIDERVRSIEVEQHRIANA 369
                   |..||:..|:....:::.|:|....:|.|           ::..:.:.::|:..:
Zfish   124 -------LSQTAEQSRKITTVEAQVINQTTRIERQL-----------LENSISTSKLEKEFL--- 167

  Fly   370 NFNLSSQIASLDKL--HTSMLEL-LEDVEGLQTKMDKSIPELRHEISKLEFANAQITSEQSLIRE 431
                 .||..::||  ..|.||. :||:||.:....:::.|.:.|:.||
Zfish   168 -----QQINEINKLKEKNSFLEKGIEDMEGKRNTELETLKEEKEELKKL---------------- 211

  Fly   432 EGTNAARSLQAMAVSVSVLQEEREGMRKLSANVDQLRTNVDRLQSLVNDEMKN-KLTHLNKPHKR 495
                       :.:...|::|..:.:...|::...::.....|.:.||:.::. .:|
Zfish   212 -----------VEMLAKVIKEMEQQVSSTSSDNTAMKQQQQELTNTVNNLIQTISVT-------- 257

  Fly   496 PHHQNVQAQMPQDDSPIDSVLAETLVSELENVETQYEAIINKLPHDCSEVHTQ---TDGLHLIAP 557
              .|...:.|.||:.  |.::                        ||:.|..|   ..|::.:..
Zfish   258 --RQGSNSAMMQDNP--DQLI------------------------DCAVVFKQGNKKSGVYSLTI 294

  Fly   558 AGQRHPLMTHC----TADGWTTVQRRFDGSADFNRSWADYAQGFGAPGGEFWIGNEQLHHLTLDN 618
            .|.:.....:|    ...|||.:|:||:|..||:::|.:|..|||...||.|:|||.:..||.:.
Zfish   295 PGTKQQFKAYCDMGTDGGGWTVIQKRFNGLVDFHQTWKNYTMGFGDISGEHWLGNEIISKLTQEK 359

  Fly   619 CSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHIAEYSGNASDALNY-QQGMQFSAIDDDRDI 682
            ...|::.:.|...|...::|.:|.:......||:.:..|||.|....:. |.|..|||.|.|.|.
Zfish   360 QHTLRIDLMDWEGNTAFSKYSQFSLDGEKQNYRISLNGYSGTAGRTSSMGQTGGDFSAKDLDNDK 424

  Fly   683 SQTHCAANYEGGWWFSHCQHANLNG----------RYNLGLTWFDAARNEW----IAVKSSRMLV 733
            ....|:....|||||..|..:||||          |:| |:.|:     .|    .::|::.|::
Zfish   425 CVCKCSQMLSGGWWFDACGPSNLNGIYYQQGQNTNRFN-GIKWY-----YWKGSAYSLKATTMMI 483

  Fly   734 KRLPA 738
            :  ||
Zfish   484 R--PA 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK03918	134..>485	CDD:235175	45/248 (18%)
		FBG	538..736	CDD:214548	66/219 (30%)
angpt2a	NP_001265754.1	SMC_N	<71..>257	CDD:481474	45/250 (18%)
		FReD	275..485	CDD:238040	66/217 (30%)