DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sca and mfap4.2

DIOPT Version :9

Sequence 1:	NP_476710.2	Gene:	sca / 36411	FlyBaseID:	FBgn0003326	Length:	799	Species:	Drosophila melanogaster
Sequence 2:	XP_012826893.1	Gene:	mfap4.2 / 100488329	XenbaseID:	XB-GENE-22167947	Length:	261	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	84/248 - (33%)
Similarity:	126/248 - (50%)	Gaps:	34/248 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   525 ENVETQYEAIINKLPHDCSEVH---TQTDGLHLIAPAGQRHPLMTHC--TAD--GWTTVQRRFDG 582
            :.::.|.:......|.||.:|:   ::.||:::|.|||....|..:|  |.|  .||.:|:||||
Frog    20 QKLKRQSDIGTGPFPADCEDVYALGSKEDGVYIIYPAGSSSALPVYCDMTTDEAKWTVIQKRFDG 84

  Fly   583 SADFNRSWADYAQGFGAPGGEFWIGNEQLHHLTLDNCSRLQVQMQDIYDNVWVAEYKRFYISSRA 647
            |..|:|.|.||..|||....|:|:|...::.|||.....|::::.|..:|...|||..|.:|..|
Frog    85 SLSFSRGWTDYKLGFGRADEEYWLGLHNIYQLTLQKKYMLRIELGDFENNTAHAEYTDFSLSPNA 149

  Fly   648 -----DGYRLHIAEY-SGNASDALNYQQGMQFSAIDDDRDISQTHCAANYEGGWWFSHCQHANLN 706
                 |||.|.:..: .|.|.|:|.:..||:||..|.|:|..|.:||..|..|:||..|..||:|
Frog   150 INPEDDGYTLFVDGFIDGGAGDSLTFHNGMKFSTFDHDQDTYQQNCAFLYSSGFWFKGCHLANIN 214

  Fly   707 GRY---------NLGLTWFDAARNEW----IAVKSSRMLVKRLPAVECQANAS 746
            |.|         ..|:||     ..|    .::|::.:.::|   ||...|.|
Frog   215 GPYLQDATYTSSGNGITW-----TRWKGFNYSLKTTEIKIRR---VEMCQNCS 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK13923	<200..300	CDD:276343
sca	NP_476710.2	FBG	538..736	CDD:214548	78/223 (35%)
mfap4.2	XP_012826893.1	FReD	32..252	CDD:238040	79/227 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H134529
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000