DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sca and fgl1

DIOPT Version :9

Sequence 1:	NP_476710.2	Gene:	sca / 36411	FlyBaseID:	FBgn0003326	Length:	799	Species:	Drosophila melanogaster
Sequence 2:	XP_001923586.2	Gene:	fgl1 / 100003029	ZFINID:	ZDB-GENE-130815-1	Length:	307	Species:	Danio rerio

Alignment Length:	278	Identity:	87/278 - (31%)
Similarity:	128/278 - (46%)	Gaps:	62/278 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   518 ETLVSELENVE---TQYEAIINKLPH-----------------------DCSEVH---TQTDGLH 553
            |.|..||.::|   |:.:.:|::|.:                       ||:::.   :.:.|.:
Zfish    28 ERLRVELRSLELRHTKQQQLIHRLMNINQMDDRSLKEGSFYDTGDTQYMDCAQIFKNGSTSSGFY 92

  Fly   554 LIAPAGQRHPLMTHCTAD-----GWTTVQRRFDGSADFNRSWADYAQGFG---APGGEFWIGNEQ 610
            :|.|.  |.|.......|     |||..|||.|||..|:|.|.||..|||   :..||||:||:.
Zfish    93 MIKPL--RSPTRVRVFCDMTEGGGWTLFQRRSDGSLSFDRDWNDYKIGFGDMKSANGEFWLGNDN 155

  Fly   611 LHHLTLDNCSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHIAEYSGNASDALN--------- 666
            ||:||......|::.::|.......|.|:.|.:.:....|:|....|||.|.|||:
Zfish   156 LHYLTSQGDYTLRINLEDFEGTHRFAVYRNFKVDNEEKHYQLQFGMYSGTAGDALSGSFHPEVQW 220

  Fly   667 --YQQGMQFSAIDDDRDISQTHCAANYEGGWWFSHCQHANLNGRYNL---------GLTWFDAAR 720
              ..|||:||..|.|.|....:||...:|||||:.|..|||||.|:.         |:.|: ...
Zfish   221 WASHQGMKFSTRDRDHDRYDRNCAQEDKGGWWFNRCHSANLNGFYHRGAYSASTDDGIVWY-PWH 284

  Fly   721 NEWIAVKSSRMLVKRLPA 738
            ..|.::||.:|.::  ||
Zfish   285 GWWYSLKSVQMKIR--PA 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sca	NP_476710.2	PRK13923	<200..300	CDD:276343
sca	NP_476710.2	FBG	538..736	CDD:214548	78/251 (31%)
fgl1	XP_001923586.2	FReD	74..299	CDD:238040	77/229 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.100