DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12374 and Agbl4

DIOPT Version :9

Sequence 1:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	XP_011238954.1	Gene:	Agbl4 / 78933	MGIID:	1918244	Length:	552	Species:	Mus musculus

Alignment Length:	312	Identity:	72/312 - (23%)
Similarity:	110/312 - (35%)	Gaps:	113/312 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 TY----HTLDTIYDWIDQECAAHDFLECKVIGQSYEGR--DIKSI----RLSKRSGNKAIFLEGN 171
            ||    |.||::      :....|:...:.:|||.:.|  |:.:|    .|.:.|..|.||:.|.
Mouse   182 TYTRFQHYLDSL------QKKNMDYFFREQLGQSVQQRQLDLLTITSPENLREGSEKKVIFITGR 240

  Fly   172 IHAMEWISSATVTFLLNQLINSEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNG 236
            :|..|..||.....:::.|: |:.|..:.|.|...:.:.||:|||| ||.             ..
Mouse   241 VHPGETPSSFVCQGIIDFLV-SQHPIARVLREHLVFKIAPMLNPDG-VYL-------------GN 290

  Fly   237 YRNESGDC--YGIDMNRNFDYHW-GGAGWNIDEPCDHWFGG---------EEPNTEVEIISLQNF 289
            ||     |  .|.|:||    || ..:.|  ..|..|   |         .:|.|.:|.
Mouse   291 YR-----CSLMGFDLNR----HWLDPSPW--AHPTLH---GVKQLIIKMYNDPKTSLEF------ 335

  Fly   290 VSSFEDGYIRSYMAYHAYGQYVL-LPYGH---------SNTEFP----PNYEQMKRIAAAFS-DA 339
                       |:..||:...:. ..||:         ..:.||    .|.|.....:.:|: ||
Mouse   336 -----------YIDIHAHSTMMNGFMYGNIFEDEERFQRQSIFPKLLCQNAEDFSYTSTSFNRDA 389

  Fly   340 AADVYGSTFTYGASGLL--------------NYVVSGAAKDWAYGVKKIPFT 377
            .....|..|   ..|||              :|::.|.       ...:|:|
Mouse   390 VKAGTGRRF---LGGLLDHSSYCYTLEVSFYSYIIGGT-------TAAVPYT 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12374	NP_610819.1	Propep_M14	34..104	CDD:280416
CG12374	NP_610819.1	M14_CP_A-B_like	118..415	CDD:199844	71/311 (23%)
Agbl4	XP_011238954.1	Pepdidase_M14_N	65..>142	CDD:375499
Agbl4	XP_011238954.1	M14_AGBL4_like	199..450	CDD:349479	67/289 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900