Protein Alignment CG12374 and Cpb1

DIOPT Version :10

• Sequence 1: NP_610819.1
• Gene: CG12374 / 36410
• FlyBaseID: FBgn0033774
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_083982.1
• Gene: Cpb1 / 76703
• MGIID: 1923953
• Length: 415
• Species: Mus musculus
• Alignment Length: 451
• Identity: 133/451 - (29%)
• Similarity: 224/451 - (49%)
• Gaps: 78/451 - (17%)

  Fly     5 ILLITLVAMVAAKSAPGRMAARYDHFRIYQLTIETNLQMEELKKIHEHISVHFLNELGAVGNKYN 69
            :||:.||::..|.::    ...:|..|:::::            :|:...|..:.||   .|...
Mouse     2 LLLLALVSVALAHAS----EENFDGNRVFRVS------------VHDEDDVSLIQEL---ANTKQ 47

  Fly    70 V---------IVGPL----FHRALEKTL---KFL---EIVYEVIVDDLQKLIDESSVGDDSQMEW 115
            :         .|.||    ||...|..:   .||   |::|||::.:::.::       :||.:.
Mouse    48 IDFWKPDSATQVKPLTTVDFHVKAEDVVDVENFLEENEVLYEVLISNVKHIL-------ESQFDS 105

  Fly   116 ET---------YHTLDTIYDWIDQECAAH-DFLECKVIGQSYEGRDIKSIRLSKRSGNK-AIFLE 169
            .|         |:..:||..||.|....: |.:..:|||.::|||::..:::.|...|| |.|::
Mouse   106 HTRASGHSYTKYNNWETIEAWIQQVANDNPDLVSKRVIGTTFEGRNMYVLKIGKDRPNKPAFFID 170

  Fly   170 GNIHAMEWISSATVTFLLNQLINS--EDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNR 232
            ...||.||||.|...:.:.:.:.:  ::..|:||.:|.|:.|:|:||.||:|||...:|:|||.|
Mouse   171 CGFHAREWISPAFCQWFVREAVRTYKQEIHMKRLLDELDFYVLPVVNIDGYVYTWAKDRMWRKTR 235

  Fly   233 RPNGYRNESGDCYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFV----SSF 293
            ....    ...|:|:|.|||||..|...|.: ..||...:.|..|.:|.|..:|.:|:    ||
Mouse   236 STTA----GSSCFGVDPNRNFDAGWCEVGAS-RSPCSDTYCGPTPESEKETKALADFIRQNLSS- 294

  Fly   294 EDGYIRSYMAYHAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYGSTFTYGASGLLNY 358
                |::|:..|:|.|.:|.||.: :.:.|.|||::..:....:...:.::|:.:|||......|
Mouse   295 ----IKAYLTVHSYSQMMLYPYSY-DYKLPENYEELNALVKGAAKELSTLHGTKYTYGPGATTIY 354

  Fly   359 VVSGAAKDWAY--GVKKIPFTCTVELRDKGTFGFFLPSNQITEVGLEVTAGLKALVNKAAE 417
            ..:|.:.||||  |:|   ::.|.||||||.|||.||.:||.:...|....:|.:.|...|
Mouse   355 PAAGGSDDWAYDQGIK---YSFTFELRDKGFFGFLLPESQIRQTCEETMLAVKYIANYVLE 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12374	NP_610819.1	Propep_M14	33..104	CDD:460505	17/89 (19%)
		M14_CP_A-B_like	118..413	CDD:349433	104/304 (34%)
Cpb1	NP_083982.1	Propep_M14	26..102	CDD:460505	17/97 (18%)
		M14_CPB	112..411	CDD:349443	105/312 (34%)