back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12374 and Cpa5

DIOPT Version :9

Sequence 1:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_653120.1	Gene:	Cpa5 / 74649	MGIID:	1921899	Length:	436	Species:	Mus musculus

Alignment Length:	346	Identity:	116/346 - (33%)
Similarity:	192/346 - (55%)	Gaps:	30/346 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 LKFLEIVYEVIVDDLQKLIDE--SSVGDDSQME-------WETYHTLDTIYDWIDQECAAHDFLE 139
            ||...:.|.:::.|:|.|:||  .::....::|       :.:|||||.||.|||...|.|..|.
Mouse    96 LKSHGLAYSIMIKDIQVLLDEERDAMAKSRRLERSTNSFSYSSYHTLDEIYSWIDNFVAEHSNLV 160

  Fly   140 CKV-IGQSYEGRDIKSIRLSKRSGNK-AIFLEGNIHAMEWISSATVTFLLNQLINS--EDPEMQR 200
            .|: ||:|:|.|.|..::.|....|: ||:::..||:.|||:.||..::..:::|:  :|..::|
Mouse   161 SKIHIGKSFENRSILVLKFSTGGPNRPAIWIDTGIHSREWITHATGIWISQKIVNAYGKDHVLKR 225

  Fly   201 LSEEYDWIVVPMVNPDGFVYTHEVERLWRKNR--RPNGYRNESGDCYGIDMNRNFDYHWGGAGWN 263
            :....|..:..:.|||||.:||.:.||||||:  :|..:      |.|:|:|||:...:||.|.|
Mouse   226 ILNTMDIFIEIVTNPDGFAFTHSMNRLWRKNKSSQPGIF------CIGVDLNRNWKAGFGGNGSN 284

  Fly   264 IDEPCDHWFGGEEPNTEVEIISLQNFVSSFEDGYIRSYMAYHAYGQYVLLPYGHSNTEFPPNYEQ 328
             ..||...:.|..|.:|.|:.::.:|::.  .|..::.::.|:|.|.|:.||||| .|..||:|:
Mouse   285 -KNPCSETYRGPAPESEPEVAAIVDFITG--HGNFKAMISIHSYSQMVMYPYGHS-LEPVPNHEE 345

  Fly   329 MKRIAAAFSDAAADVYGSTFTYGASGLLNYVVSGAAKDWAY--GVKKIPFTCTVELRDKGTFGFF 391
            :..:|.....|...|:|..:.:|:.....|..||.:.||||  |:|   :..:.||||.|.:||.
Mouse   346 LFNLAKDAVKALNKVHGIQYIFGSISTTLYSASGISVDWAYDSGIK---YAFSFELRDTGQYGFL 407

  Fly   392 LPSNQITEVGLEVTAGLKALV 412
            ||::||.....|....|:.::
Mouse   408 LPASQIVPTAEETWMALQTIM 428

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.