DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12374 and Agtpbp1

DIOPT Version :9

Sequence 1:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001364026.1	Gene:	Agtpbp1 / 67269	MGIID:	2159437	Length:	1218	Species:	Mus musculus

Alignment Length:	279	Identity:	61/279 - (21%)
Similarity:	84/279 - (30%)	Gaps:	115/279 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 YEVIVDDLQKLIDESSVGDDSQMEWETYHTLDTIYDWIDQECAAHDFLECKVI-------GQSYE 148
            |..:...||||              |:.|....||...|..|.......|.::       ...||
Mouse   844 YSTLQMHLQKL--------------ESAHNPQQIYFRKDVLCETLSGNICPLVTITAMPESNYYE 894

  Fly   149 GRDIKSIRLSKRSGNKAIFLEGNIHAME----WISSATVTFLLNQLINSEDPEMQRLSEEYDWIV 209
                   .:.:......|||...:|..|    |:...|:.:|:     |..|..|.|.|.|.:.:
Mouse   895 -------HICQFRTRPYIFLSARVHPGETNASWVMKGTLEYLM-----SNSPTAQSLRESYIFKI 947

  Fly   210 VPMVNPDGFVYTHEVERLWRKNRRPNGYRNESGDCYGIDMNRNFDYHWGGAGWNIDEPCDHWFGG 274
            |||:||||.:               ||  |......|.|:||                  .|
Mouse   948 VPMLNPDGVI---------------NG--NHRCSLSGEDLNR------------------QW--- 974

  Fly   275 EEPNTEVEIISLQNFVSSFEDGYIRSYMAYHAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDA 339
            :.||.|:.                  ...|||.|   ||.|          ...:||:...:
Mouse   975 QSPNPELH------------------PTIYHAKG---LLQY----------LAAVKRLPLVY--- 1005

  Fly   340 AADVYG-----STFTYGAS 353
             .|.:|     :.|.||.|
Mouse  1006 -CDYHGHSRKKNVFMYGCS 1023

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12374	NP_610819.1	Propep_M14	34..104	CDD:280416	5/12 (42%)
CG12374	NP_610819.1	M14_CP_A-B_like	118..415	CDD:199844	55/252 (22%)
Agtpbp1	NP_001364026.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	476..512
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	590..617
		Pepdidase_M14_N	704..838	CDD:407865
		M14_Nna1	861..1131	CDD:349477	54/248 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1193..1218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900