Protein Alignment CG12374 and AGBL5

DIOPT Version :9

• Sequence 1: NP_610819.1
• Gene: CG12374 / 36410
• FlyBaseID: FBgn0033774
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_068603.4
• Gene: AGBL5 / 60509
• HGNCID: 26147
• Length: 886
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 87/437 - (19%)
• Similarity: 134/437 - (30%)
• Gaps: 168/437 - (38%)

  Fly    77 HRALE--KTLKFLEIVYEVIVDDLQKLIDESSVGDDSQMEWETYHT--LDTIYDWIDQECAAHDF 137
            ||.:|  ....|....|.....|.|:|:::.   |....|....|:  |||||...:..|.:.|.
Human   141 HRFVEGRGATTFFAFCYPFSYSDCQELLNQL---DQRFPENHPTHSSPLDTIYYHRELLCYSLDG 202

  Fly   138 L--------ECKVIGQSYEGR------DIKSIRLSKRSGNKAIFLEGNIHAMEWISSATVTFLLN 188
            |        .|..:.:..|.|      |..:.|..:.:|.:..||...:|..|..||......|:
Human   203 LRVDLLTITSCHGLREDREPRLEQLFPDTSTPRPFRFAGKRIFFLSSRVHPGETPSSFVFNGFLD 267

  Fly   189 QLINSEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNGYRNESGDCYGIDMNRNF 253
            .::..:||..|.|...:.:.::||:||||.|..|              ||.:|   .|:::||.:
Human   268 FILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRGH--------------YRTDS---RGVNLNRQY 315

  Fly   254 ----------------------------------------------------------------- 253
                                                                             
Human   316 LKPDAVLHPAIYGAKAVLLYHHVHSRLNSQSSSEHQPSSCLPPDAPVSDLEKANNLQNEAQCGHS 380

  Fly   254 -DYHWGGAGWNIDEPCDH-----WF------GGEE--PNTEVEIISLQNFVSSFEDGYIRSYMAY 304
             |.| ....|...||.:.     |.      |.||  |:|          :...|.| :..|:..
Human   381 ADRH-NAEAWKQTEPAEQKLNSVWIMPQQSAGLEESAPDT----------IPPKESG-VAYYVDL 433

  Fly   305 HAY----GQYVLLPYGHSNTEFPPNYEQM---KRIAAAFSDAAADVYGSTFT------------- 349
            |.:    |.::   ||:|.::.....|.|   |.|  :.:.|..|..|..|:
Human   434 HGHASKRGCFM---YGNSFSDESTQVENMLYPKLI--SLNSAHFDFQGCNFSEKNMYARDRRDGQ 493

  Fly   350 ----------YGASGLLNYVVSGAAKDWAYGVKKIPFTCTVELRDKG 386
                      |.|||:::........:....|..||..|    .|.|
Human   494 SKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAAC----HDNG 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12374	NP_610819.1	Propep_M14	34..104	CDD:280416	8/28 (29%)
		M14_CP_A-B_like	118..415	CDD:199844	77/394 (20%)
AGBL5	NP_068603.4	M14_AGBL5_like	176..568	CDD:199860	78/399 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	344..364		0/19 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	605..734
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	784..848

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810