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Protein Alignment CG12374 and CPA6

DIOPT Version :9

Sequence 1:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_065094.3	Gene:	CPA6 / 57094	HGNCID:	17245	Length:	437	Species:	Homo sapiens

Alignment Length:	403	Identity:	124/403 - (30%)
Similarity:	202/403 - (50%)	Gaps:	31/403 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RYDHFRIYQLTIETNLQMEELKKIHEHI--------SVHFLNELGAVGNKYNVIVGPLFHRALEK 82
            ||...::.:...:|..:...||||...:        |:.:::|    |...:|.:.....|||..
Human    36 RYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSE----GTVTDVHIPQNGSRALLA 96

  Fly    83 TLKFLEIVYEVIVDDLQKLIDE-SSVGDD------SQMEWETYHTLDTIYDWIDQECAAHD-FLE 139
            .|:...|.|:|:::||||.::: ||:...      |...:|.||:|:.|.:|:......|. .:.
Human    97 FLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIH 161

  Fly   140 CKVIGQSYEGRDIKSIRLSKRSG-NKAIFLEGNIHAMEWISSATVTFLLNQ--LINSEDPEMQRL 201
            ...||:|||||.:..::|.:||. .:|::::..|||.|||..|...:.:.:  |....||.|:::
Human   162 MFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKM 226

  Fly   202 SEEYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNGYRNESGDCYGIDMNRNFDYHWGGAGWNIDE 266
            .....:.::|:.|.||:.::...:|.|||.|.    ||....|.|:|.|||:...|...|.:: .
Human   227 LNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRS----RNSRFRCRGVDANRNWKVKWCDEGASM-H 286

  Fly   267 PCDHWFGGEEPNTEVEIISLQNFVSSFEDGYIRSYMAYHAYGQYVLLPYGHSNTEFPPNYEQMKR 331
            |||..:.|..|.:|.|:.::.||:..... :||:|:::|||.|.:|.||.:..... ||:..::.
Human   287 PCDDTYCGPFPESEPEVKAVANFLRKHRK-HIRAYLSFHAYAQMLLYPYSYKYATI-PNFRCVES 349

  Fly   332 IAAAFSDAAADVYGSTFTYGASGLLNYVVSGAAKDWAYGVKKIPFTCTVELRDKGTFGFFLPSNQ 396
            .|....:|...|||..:.||.:....||.||::.|||| ...||:....||||.|.|||.||...
Human   350 AAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAY-KNGIPYAFAFELRDTGYFGFLLPEML 413

  Fly   397 ITEVGLEVTAGLK 409
            |.....|....:|
Human   414 IKPTCTETMLAVK 426

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.