Protein Alignment CG12374 and Cpa6

DIOPT Version :10

• Sequence 1: NP_610819.1
• Gene: CG12374 / 36410
• FlyBaseID: FBgn0033774
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_011236694.1
• Gene: Cpa6 / 329093
• MGIID: 3045348
• Length: 459
• Species: Mus musculus
• Alignment Length: 381
• Identity: 102/381 - (26%)
• Similarity: 185/381 - (48%)
• Gaps: 57/381 - (14%)

  Fly     3 LPI--LLITLVAMVAAKSAPGRMAA---RYDHFRIYQLTIETNLQMEELKKIHEHI--------S 54
            ||:  ||:.::       .||...:   ||...::.:|..::..:...||.|:..:        |
Mouse    15 LPVCWLLLNIL-------KPGHCHSYDNRYAGDKVIRLIPKSEEEALALKNIYHQLKVDLWQPSS 72

  Fly    55 VHFLNELGAVGNKYNVIVGPLFHRALEKTLKFLEIVYEVIVDDLQKLID-ESSVGDD------SQ 112
            :.:::|    |...:|.:.....|.|...|:...|.|:|:::||||.:: |:|:...      |:
Mouse    73 ISYVSE----GTITDVHISQNASRTLLAFLQETHIYYKVLIEDLQKAVENENSLQTQRNRRSLSE 133

  Fly   113 MEWETYHTLDTIYDWIDQECAAHDFLECK-------VIGQSYEGRDIKSIRLSKRSG--NKAIFL 168
            ..:|.||:|:.|..|:      |...:.:       .||:|||||.:..::|.::|.  .:|:::
Mouse   134 YNYEVYHSLEDIQSWL------HHLNQTQPGLVRVFSIGRSYEGRPLFIMQLGRKSRAYKRAVWI 192

  Fly   169 EGNIHAMEWISSATVTFLLNQ--LINSEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKN 231
            :..|||.|||..|...:.:.:  |....||.|:::.....:.::|:.|.||:.::...:|.|||.
Mouse   193 DCGIHAREWIGPAFCQWFVREAILTYKTDPAMKKMLNHLYFYIMPVFNVDGYHFSWTHDRFWRKT 257

  Fly   232 R-RPNGYRNESGDCYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFVSSFED 295
            | |.:.:|     |.|:|.|||:...|...|.:. .|||..:.|..|.:|.|:.::.||:.....
Mouse   258 RSRDSKFR-----CRGVDANRNWKVKWCDEGASA-HPCDDTYCGPFPESEPEVKAVANFLRKHRK 316

  Fly   296 GYIRSYMAYHAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYGSTFTYG 351
             .||:|:::|||.|.:|.||.:..... ||:..::..|.....|...|:|..:.:|
Mouse   317 -RIRAYLSFHAYAQMLLYPYSYKYATI-PNFSCVEFAAHKAVKALRSVHGIRYRHG 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12374	NP_610819.1	Propep_M14	33..104	CDD:460505	18/79 (23%)
		M14_CP_A-B_like	118..413	CDD:349433	72/246 (29%)
Cpa6	XP_011236694.1	Propep_M14	43..119	CDD:460505	18/79 (23%)
		Peptidase_M14_like	138..382	CDD:472171	72/247 (29%)