DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12374 and CG31019

DIOPT Version :9

Sequence 1:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_733391.1	Gene:	CG31019 / 318558	FlyBaseID:	FBgn0051019	Length:	659	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	64/270 - (23%)
Similarity:	106/270 - (39%)	Gaps:	74/270 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 MEWE-TYHTLDTIYDWID-QECAAHDFLECKVIGQSYEGRD-----IKSIRLSKRSGN------- 163
            :.|. :|..|.:..:.|| ::.:...|..| |:.:|.:.|:     |..:...:||.|
  Fly   174 LAWPYSYSRLQSYLNVIDARQGSDKRFTRC-VLVKSLQNRNVDLLTIDHVTAKQRSTNRLDRSFI 237

  Fly   164 KAIFLEGNIHAMEWISSATVTFLLNQLINSEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLW 228
            :.|.:....|:.|..:|.....|:..|:.:. |....|.:.:.:.:||||||||         ::
  Fly   238 RVIVVLCRTHSSEAPASHVCQGLIEFLVGNH-PIAAVLRDNFVFKIVPMVNPDG---------VF 292

  Fly   229 RKNRRPNGYRNESGDCYGIDMNRNFDYHWGGAGWNIDEPCDHWFGG---EEPNTEVE-------- 282
            ..|.|.|        ..|.|||||  :|.|.   ...:|..|...|   |..|::|.
  Fly   293 LGNNRCN--------LMGQDMNRN--WHIGS---EFTQPELHAVKGMLKELDNSDVSRGIETDLI 344

  Fly   283 -IISLQNFVSSFEDGYIRSYMAYHA----YGQYVLLPYGHSNTEFPPNYEQMKR----------I 332
             ||.:.::..||:...|...:..||    :|.::   ||::       ||.:.|          .
  Fly   345 GIIFVCSYNISFQTYQIDFVIDLHANSSMHGCFI---YGNT-------YEDVYRYERHLVFPRLF 399

  Fly   333 AAAFSDAAAD 342
            |:...|..||
  Fly   400 ASNAQDYVAD 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12374	NP_610819.1	Propep_M14	34..104	CDD:280416
CG12374	NP_610819.1	M14_CP_A-B_like	118..415	CDD:199844	63/264 (24%)
CG31019	NP_733391.1	M14_AGBL4_like	190..478	CDD:133118	61/254 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900