DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12374 and Cpa6

DIOPT Version :9

Sequence 1:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	XP_038965675.1	Gene:	Cpa6 / 312913	RGDID:	1311764	Length:	290	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	90/271 - (33%)
Similarity:	143/271 - (52%)	Gaps:	12/271 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 IGQSYEGRDIKSIRLSKRSG--NKAIFLEGNIHAMEWISSATVTFLLNQ--LINSEDPEMQRLSE 203
            ||:|:|||.:..|:|.::|.  .:|::::..|||.|||..|...:.:.:  |....||.|:::..
  Rat    17 IGRSFEGRSLLIIQLGRKSQVYKRAVWIDCGIHAREWIGPAFCQWFVKEAILTYKTDPAMRKMLN 81

  Fly   204 EYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNGYRNESGDCYGIDMNRNFDYHWGGAGWNIDEPC 268
            ...:.::|::|.||:.::...:|.|||.|.    ||....|.|:|.|||:...|...|.:.| ||
  Rat    82 HLYFYIMPVLNVDGYHFSWTHDRFWRKTRS----RNSKFHCRGVDANRNWKVKWCDEGASAD-PC 141

  Fly   269 DHWFGGEEPNTEVEIISLQNFVSSFEDGYIRSYMAYHAYGQYVLLPYGHSNTEFPPNYEQMKRIA 333
            |..:.|..|.:|.|:.::.||:..... .||:|:::|||.|.:|.||.:.:... ||:..::..|
  Rat   142 DDTYCGPFPESEPEVKAVANFLRKHRK-RIRAYLSFHAYAQMLLYPYSYKHATI-PNFSCVEFAA 204

  Fly   334 AAFSDAAADVYGSTFTYGASGLLNYVVSGAAKDWAYGVKKIPFTCTVELRDKGTFGFFLPSNQIT 398
            .....|...|:|..:.:|.:....||.||.:.|||| ...||::...||||.|.|||.||...|.
  Rat   205 HKAVKALRSVHGIRYRHGPASQTLYVSSGNSMDWAY-KNGIPYSFAFELRDTGYFGFLLPEMLIK 268

  Fly   399 EVGLEVTAGLK 409
            ....|....:|
  Rat   269 PTCTETMLAVK 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12374	NP_610819.1	Propep_M14	34..104	CDD:280416
CG12374	NP_610819.1	M14_CP_A-B_like	118..415	CDD:199844	90/271 (33%)
Cpa6	XP_038965675.1	Peptidase_M14_like	1..289	CDD:416253	90/271 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351701
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3014
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.800