Protein Alignment CG12374 and Cpa6

DIOPT Version :10

• Sequence 1: NP_610819.1
• Gene: CG12374 / 36410
• FlyBaseID: FBgn0033774
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001402791.1
• Gene: Cpa6 / 312913
• RGDID: 1311764
• Length: 438
• Species: Rattus norvegicus
• Alignment Length: 436
• Identity: 126/436 - (28%)
• Similarity: 211/436 - (48%)
• Gaps: 52/436 - (11%)

  Fly     3 LPILLITLVAMVAAKSAPGRMAA---RYDHFRIYQLTIETNLQMEELKKIHEHI--------SVH 56
            ||:..:.|..:     .||...:   ||...::.:|..::..:...||.:...:        |:.
  Rat    15 LPVCCLLLKIL-----QPGHCHSYDNRYAGHKVIRLIPKSEEEALALKSVSHQLKVDLWQPSSIS 74

  Fly    57 FLNELGAVGNKYNVIVGPLFHRALEKTLKFLEIVYEVIVDDLQKLID-ESSVGDD------SQME 114
            :::|    |...:|.|.....|.|...|:...|.|:|:::||||.:: |:||...      |:..
  Rat    75 YVSE----GTITDVRVTQNASRTLLAILQETNIQYKVLIEDLQKAVENENSVHTQRNRRSLSEYN 135

  Fly   115 WETYHTLDTIYDWIDQECAAHDFLECK-------VIGQSYEGRDIKSIRLSKRSG--NKAIFLEG 170
            :|.||:|:.|..|:      |...:.:       .||:|:|||.:..|:|.::|.  .:|::::.
  Rat   136 YEVYHSLEDIQSWM------HHLNQTQPGLVRVFPIGRSFEGRSLLIIQLGRKSQVYKRAVWIDC 194

  Fly   171 NIHAMEWISSATVTFLLNQ--LINSEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNRR 233
            .|||.|||..|...:.:.:  |....||.|:::.....:.::|::|.||:.::...:|.|||.|.
  Rat   195 GIHAREWIGPAFCQWFVKEAILTYKTDPAMRKMLNHLYFYIMPVLNVDGYHFSWTHDRFWRKTRS 259

  Fly   234 PNGYRNESGDCYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFVSSFEDGYI 298
                ||....|.|:|.|||:...|...|.:.| |||..:.|..|.:|.|:.::.||:..... .|
  Rat   260 ----RNSKFHCRGVDANRNWKVKWCDEGASAD-PCDDTYCGPFPESEPEVKAVANFLRKHRK-RI 318

  Fly   299 RSYMAYHAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYGSTFTYGASGLLNYVVSGA 363
            |:|:::|||.|.:|.||.:.:... ||:..::..|.....|...|:|..:.:|.:....||.||.
  Rat   319 RAYLSFHAYAQMLLYPYSYKHATI-PNFSCVEFAAHKAVKALRSVHGIRYRHGPASQTLYVSSGN 382

  Fly   364 AKDWAYGVKKIPFTCTVELRDKGTFGFFLPSNQITEVGLEVTAGLK 409
            :.|||| ...||::...||||.|.|||.||...|.....|....:|
  Rat   383 SMDWAY-KNGIPYSFAFELRDTGYFGFLLPEMLIKPTCTETMLAVK 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12374	NP_610819.1	Propep_M14	33..104	CDD:460505	18/79 (23%)
		M14_CP_A-B_like	118..413	CDD:349433	96/303 (32%)
Cpa6	NP_001402791.1	Propep_M14	43..119	CDD:460505	18/79 (23%)
		Peptidase_M14_like	138..437	CDD:472171	96/304 (32%)