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Protein Alignment CG12374 and Cpa2

DIOPT Version :9

Sequence 1:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001013101.2	Gene:	Cpa2 / 296959	RGDID:	1305563	Length:	417	Species:	Rattus norvegicus

Alignment Length:	435	Identity:	132/435 - (30%)
Similarity:	223/435 - (51%)	Gaps:	49/435 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLPILLITLVAMVAAKSA----------PGRMAARYDHFRIYQLTIETNLQMEELKKIHEHISV 55
            |:|.:||..|:..:..:..          |.           ::..|.|.||:|    ..||:.:
  Rat     1 MRLTLLLAALLGYIYCQETFVGDQVLEIIPS-----------HEEQIRTLLQLE----AEEHLEL 50

  Fly    56 HFLNELGAVGNKYNVIVGPLFHRALEKTLKFLEIVYEVIVDDLQKLIDE--SSVGDDSQME---- 114
            .|.......|...:|.|.....:|::..|:...|.|.::::|:|.|:|:  ..:..:.|.|
  Rat    51 DFWKSPTIPGETVHVRVPFASIQAVKVFLESQGIDYSIMIEDVQVLLDQEREEMLFNQQRERGGN 115

  Fly   115 --WETYHTLDTIYDWIDQECAAHDFLECKV-IGQSYEGRDIKSIRLSKRSGNKAIFLEGNIHAME 176
              :|.||||:.||..:|...|.:..|..|| ||.|:|.|.:..::.|......||:|:..|||.|
  Rat   116 FNFEAYHTLEEIYQEMDNLVAENPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHARE 180

  Fly   177 WISSATVTFLLNQLIN--SEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNGYRN 239
            |::.||..:..|::.:  ..||.:..|....|..::|:.||||:|::....|:|||.|   ..|:
  Rat   181 WVTQATALWTANKIASDYGTDPAITSLLNTLDIFLLPVTNPDGYVFSQTTNRMWRKTR---SKRS 242

  Fly   240 ESGDCYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFVSSFEDGYIRSYMAY 304
            .|| |.|:|.|||:|.::||.|.: ..||...:.|.:||:|||:.|:.:|:.|  .|.:::::..
  Rat   243 GSG-CVGVDPNRNWDANFGGPGAS-SSPCSDSYHGPKPNSEVEVKSIVDFIKS--HGKVKAFITL 303

  Fly   305 HAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYGSTFTYGASGLLNYVVSGAAKDWAY 369
            |:|.|.::.|||:..|: |.::.::..:|...:.|...::|:::..|....:.|..||.:.||||
  Rat   304 HSYSQLLMFPYGYKCTK-PDDFNELDEVAQKAAQALKRLHGTSYKVGPICSVIYQASGGSIDWAY 367

  Fly   370 --GVKKIPFTCTVELRDKGTFGFFLPSNQITEVGLEVTAGLKALV 412
              |:|   ::...||||.|.:||.||:.||.....|...|||.::
  Rat   368 DLGIK---YSFAFELRDTGFYGFLLPAKQILPTAEETWLGLKTIM 409

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.