Protein Alignment CG12374 and cpa5

DIOPT Version :10

• Sequence 1: NP_610819.1
• Gene: CG12374 / 36410
• FlyBaseID: FBgn0033774
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_954965.1
• Gene: cpa5 / 246092
• ZFINID: ZDB-GENE-020514-1
• Length: 419
• Species: Danio rerio
• Alignment Length: 442
• Identity: 124/442 - (28%)
• Similarity: 221/442 - (50%)
• Gaps: 61/442 - (13%)

  Fly     1 MKLPILLITLVAMVAAKSAPGRMAARYDHFRIYQLTIETNLQMEELKKI---HEHISVHFLNELG 62
            ||..::||.|...|..|..       ::..:::::|.:...|::.||::   .||:.:
Zfish     1 MKRLLVLIALFVAVFGKKT-------FEGDQVFRITPKDEAQIDLLKELTEEGEHLGL------- 51

  Fly    63 AVGNKYNVIVGPL-----------FH--RALEKTLKFLEIVYEVIVDDLQKLIDESS-------- 106
                  :|.:.|:           ||  :|:...|.:.:|.|.::::::|:|:|:..
Zfish    52 ------SVWMEPILESLPLDLHVPFHSLQAVRAFLAYNQIPYHIMIENVQELLDDEQRDMVKYRG 110

  Fly   107 -VGDDSQMEWETYHTLDTIYDWIDQECAAHDFLECK-VIGQSYEGRDIKSIRLSKRSGNKAIFLE 169
             ........:.|||.|::|..::|...|.:..:..| |||||||.|.:..::.|..:....|:::
Zfish   111 LARSTDDFVYTTYHDLNSINSFMDMLVAENRNMVSKVVIGQSYEKRPLNVLKFSTGANRPGIWID 175

  Fly   170 GNIHAMEWISSATVTFLLNQLIN--SEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNR 232
            ..||:.||::.|:..:...:::.  ..||.:..:...:|..:..:.|||||||||..:|:|||.|
Zfish   176 TGIHSREWVTQASGVWFAKKIVKDYGRDPVLTDILNSHDIFLEIVTNPDGFVYTHTKDRMWRKTR 240

  Fly   233 RPNGYRNESGDCYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFVSSFEDGY 297
            :|    |....|.|:|.|||:|..:||.| :.:.||...:.|...::|.|:.::.:||.|  .|.
Zfish   241 KP----NPGSSCVGVDPNRNWDAGFGGGG-SSNNPCTETYRGPSAHSEPEVKAIVDFVKS--HGK 298

  Fly   298 IRSYMAYHAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYGSTFTYGASGLLNYVVSG 362
            |:::::.|:|.|.:|.|||::.|......| :..:|.....:...:|.:.:|||:.....|..||
Zfish   299 IKAFVSIHSYSQMLLYPYGYTYTAAKDKAE-LHEVARKAITSLQSLYNTRYTYGSIITTIYQASG 362

  Fly   363 AAKDWAY--GVKKIPFTCTVELRDKGTFGFFLPSNQITEVGLEVTAGLKALV 412
            ...||.|  |:|   ::.|.||||.|.:||.||:|||.....|....|.|::
Zfish   363 GTIDWTYNQGIK---YSYTFELRDTGRYGFILPANQIVPTAEETWLALMAIM 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12374	NP_610819.1	Propep_M14	33..104	CDD:460505	16/86 (19%)
		M14_CP_A-B_like	118..413	CDD:349433	99/300 (33%)
cpa5	NP_954965.1	Propep_M14	26..101	CDD:460505	17/87 (20%)
		M14_CPA	118..417	CDD:349442	100/305 (33%)