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Protein Alignment CG12374 and Cpa1

DIOPT Version :9

Sequence 1:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_058694.2	Gene:	Cpa1 / 24269	RGDID:	2388	Length:	419	Species:	Rattus norvegicus

Alignment Length:	433	Identity:	133/433 - (30%)
Similarity:	232/433 - (53%)	Gaps:	44/433 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KLPILLITLVAMVAAKSAPGRMAARYDHFRIYQLTIETNLQMEELKKIH--EHISVHFLNELGAV 64
            :|.||.:.|.|:...::..|.        ::.:::.....|::::|::.  ||:.:.|..:....
  Rat     3 RLLILSLLLEAVCGNENFVGH--------QVLRISAADEAQVQKVKELEDLEHLQLDFWRDAARA 59

  Fly    65 GNKYNVIVGPLFHRALEKTLKFLE---IVYEVIVDDLQKLIDES----------SVGDDSQMEWE 116
            |...:|.| |.  .:::....|||   |.||::::|:|.|:||.          ::..|| ..:.
  Rat    60 GIPIDVRV-PF--PSIQSVKAFLEYHGISYEIMIEDVQLLLDEEKQQMSAFQARALSTDS-FNYA 120

  Fly   117 TYHTLDTIYDWIDQECAAHDFLECKV-IGQSYEGRDIKSIRLSKRSGNK-AIFLEGNIHAMEWIS 179
            ||||||.||:::|...|.|..|..|: ||.::|||.|..::.|....|: ||:::..||:.||::
  Rat   121 TYHTLDEIYEFMDLLVAEHPQLVSKIQIGNTFEGRPIHVLKFSTGGTNRPAIWIDTGIHSREWVT 185

  Fly   180 SATVTFLLNQLIN--SEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNGYRNESG 242
            .|:..:...::..  .:||....:.:..|..:..:.|||||.|||:..|:|||.|.    ..:..
  Rat   186 QASGVWFAKKITKDYGQDPTFTAVLDNMDIFLEIVTNPDGFAYTHKTNRMWRKTRS----HTQGS 246

  Fly   243 DCYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFVSSFEDGYIRSYMAYHAY 307
            .|.|:|.|||:|..:|.||.: ..||...:.|:.||:|||:.|:.:||:|  .|.|:::::.|:|
  Rat   247 LCVGVDPNRNWDAGFGMAGAS-SNPCSETYRGKFPNSEVEVKSIVDFVTS--HGNIKAFISIHSY 308

  Fly   308 GQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYGSTFTYGASGLLNYVVSGAAKDWAY--G 370
            .|.:|.|||:: :|..|:..::.::|.:...|...::|:.|.||:.....|..||:..||.|  |
  Rat   309 SQLLLYPYGYT-SEPAPDQAELDQLAKSAVTALTSLHGTKFKYGSIIDTIYQASGSTIDWTYSQG 372

  Fly   371 VKKIPFTCTVELRDKGTFGFFLPSNQITEVGLEVTAGLKALVN 413
            :|   ::.|.||||.|..||.||::||.....|....|..:::
  Rat   373 IK---YSFTFELRDTGLRGFLLPASQIIPTAEETWLALLTIMD 412

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.