back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12374 and Cpa2

DIOPT Version :9

Sequence 1:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001019869.1	Gene:	Cpa2 / 232680	MGIID:	3617840	Length:	417	Species:	Mus musculus

Alignment Length:	393	Identity:	124/393 - (31%)
Similarity:	206/393 - (52%)	Gaps:	36/393 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 IETNLQMEELKKIHEHISVHFLNELGAVGNKYNVIVGPLFHRALEKTLKFLE---IVYEVIVDDL 98
            |:|.||:|    ..||:.:.|...........:|.| |.  .:::....|||   |.|.::::|:
Mouse    36 IKTLLQLE----AEEHLELDFWKSPSVPRQTVHVRV-PF--ASIQDVKVFLESQGITYSIMIEDV 93

  Fly    99 QKLIDE--SSVGDDSQMEWET------YHTLDTIYDWIDQECAAHDFLECKV-IGQSYEGRDIKS 154
            |.|:|:  ..:..:.|.|..|      ||||:.||..:|...|.:..|..|| ||.|:|.|.:..
Mouse    94 QVLLDQEREEMLFNQQRERGTNFNFGAYHTLEEIYQEMDNLVAENPGLVSKVNIGSSFENRPMNV 158

  Fly   155 IRLSKRSGNKAIFLEGNIHAMEWISSATVTFLLNQLIN--SEDPEMQRLSEEYDWIVVPMVNPDG 217
            ::.|......||:|:..|||.||::.||..:..|::.:  ..||.:..|....|..::|:.||||
Mouse   159 LKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIASDYGTDPAITSLLNTLDVFLLPVTNPDG 223

  Fly   218 FVYTHEVERLWRKNRRPNGYRNESGD-CYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEV 281
            :|::....|:|||.|     ...||. |.|:|.|||:|.::||.|.: ..||...:.|..||:||
Mouse   224 YVFSQTSNRMWRKTR-----SKRSGSFCVGVDPNRNWDANFGGPGAS-SNPCSDSYHGPSPNSEV 282

  Fly   282 EIISLQNFVSSFEDGYIRSYMAYHAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYGS 346
            |:.|:.:|:.|  .|.:::::..|:|.|.::.|||:...: |.::.::..:|...:.:...::|:
Mouse   283 EVKSIVDFIKS--HGKVKAFITLHSYSQLLMFPYGYKCAK-PDDFNELDEVAQRAAQSLKRLHGT 344

  Fly   347 TFTYGASGLLNYVVSGAAKDWAY--GVKKIPFTCTVELRDKGTFGFFLPSNQITEVGLEVTAGLK 409
            ::..|....:.|..||.:.||||  |:|   ::...||||.|.:||.||:.||.....|...|||
Mouse   345 SYKVGPICSVIYQASGGSIDWAYDLGIK---YSFAFELRDTGYYGFLLPAKQILPTAEETWLGLK 406

  Fly   410 ALV 412
            .::
Mouse   407 TIM 409

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.