Protein Alignment CG12374 and T06A4.1

DIOPT Version :9

• Sequence 1: NP_610819.1
• Gene: CG12374 / 36410
• FlyBaseID: FBgn0033774
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_871809.1
• Gene: T06A4.1 / 171669
• WormBaseID: WBGene00020281
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 455
• Identity: 130/455 - (28%)
• Similarity: 228/455 - (50%)
• Gaps: 62/455 - (13%)

  Fly     1 MKLPILLITLVAMVAAKSAPGRM--AARYDHFRIYQLTIETNLQMEELKKIHEHISVHFLN---- 59
            |:||.:|:...|......|....  .|.|.:|::.::..||...::.|:.::|..|.:.|:
 Worm     1 MRLPSILLIFGAFFGFLGAIHNTDDNAGYHNFKLIRINPETEGSVKYLRSLYEDPSPYELDFWQP 65

  Fly    60 --ELGAVGNKYNVIVGPLFHRALEKTLKFLEIVYEVIVDDLQKLIDESSVGDD------SQMEWE 116
              .:||:   .::.|.|.......|.|:..:|.|.|.|:||.|.| |:..|.|      :...::
 Worm    66 PTNIGAI---VDLTVAPADAPRFVKDLESKKISYIVAVNDLSKAI-ENERGSDKFYNPVAGFAYD 126

  Fly   117 TYHTLD--------------TIYDWIDQECAAHDFLECKVIGQSYEGRDIKSIRLS-KRS--GNK 164
            .|::|:              |:...||             ||||:|.|.:..:::: ||:  |:|
 Worm   127 KYNSLEEIQTEMKRLKKEYPTMITLID-------------IGQSHENRTLLVMKITGKRNPLGSK 178

  Fly   165 -AIFLEGNIHAMEWISSATVTFLLNQLI--NSEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVER 226
             :::::..|||.|||:.||..::.::|:  ...|..:.:|.:..|:.::|::||||:.|:.|..|
 Worm   179 ISMWIDAGIHAREWIAPATAMYIAHELLLGYENDATVAKLMDHIDFYILPVMNPDGYEYSREKNR 243

  Fly   227 LWRKNRRPNGYRNESGD---CYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQN 288
            :|||||.|.....::..   |.|:|:|||||:.|...|.:.| ||...:.|....:|.|..::::
 Worm   244 MWRKNRSPAKCARQTFSTVCCSGVDLNRNFDWFWASTGSSSD-PCHDTYHGSAAFSEPESQAVRD 307

  Fly   289 FVSSFEDGYIRSYMAYHAYGQYVLLPYGHSNTEFPPNYEQ-MKRIAAAFSDAAADVYGSTFTYGA 352
            |:   |.....::::.|:|.|..|:||||....:|.:|.. ::.:|...:.|..::||:.:..|.
 Worm   308 FL---EQNTPEAFISLHSYSQMWLIPYGHRKQSYPQDYHTGLRPLALRATKALYELYGTKYQVGT 369

  Fly   353 SGLLNYVVSGAAKDWAYGVKKIPFTCTVELRDKGTF---GFFLPSNQITEVGLEVTAGLKALVNK 414
            ...|.|..||.:.|||.|..|:|:...:|||.|.|.   ||.||..:|...|||....:|.:.::
 Worm   370 GADLMYEASGGSHDWAKGQLKVPYAYLIELRPKNTMMGHGFLLPEREIVPTGLETFESIKVVADE 434

  Fly   415  414
             Worm   435  434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12374	NP_610819.1	Propep_M14	34..104	CDD:280416	20/75 (27%)
		M14_CP_A-B_like	118..415	CDD:199844	98/324 (30%)
T06A4.1	NP_871809.1	Propep_M14	40..110	CDD:366995	21/73 (29%)
		M14_CP_A-B_like	128..435	CDD:349433	98/324 (30%)
		ShK	568..602	CDD:366702

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165681
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850