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Protein Alignment CG12374 and CPB2

DIOPT Version :9

Sequence 1:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001863.3	Gene:	CPB2 / 1361	HGNCID:	2300	Length:	423	Species:	Homo sapiens

Alignment Length:	374	Identity:	107/374 - (28%)
Similarity:	183/374 - (48%)	Gaps:	43/374 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 VHFLNELGAVGNKYNVIVGPLFHRALEKTLKFLEIVYEVIVDDLQKLIDESSVGDD-----SQME 114
            |||......|.|             ::..|....|...|::.|::.||.:....|.     |...
Human    68 VHFFVNASDVDN-------------VKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY 119

  Fly   115 WETYHTLDTIYDWIDQECAAHDFLECKV-IGQSYEGRDIKSIRLS--KRSGNKAIFLEGNIHAME 176
            :|.||:|:.||.||:.....|..:..|: ||.|:|...:..:::|  :::...||:::..|||.|
Human   120 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHARE 184

  Fly   177 WISSATVTFLLNQL-----INSEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNG 236
            |||.|...:.:..:     |..:...:.||   .|:.|:|:||.||:.|:.:..|:|||||  :.
Human   185 WISPAFCLWFIGHITQFYGIIGQYTNLLRL---VDFYVMPVVNVDGYDYSWKKNRMWRKNR--SF 244

  Fly   237 YRNESGDCYGIDMNRNF-DYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFVSSFEDGYIRS 300
            |.|  ..|.|.|:|||| ..||...|.: ...|...:.|..|.:|.|:.::.:|:.. ....|::
Human   245 YAN--NHCIGTDLNRNFASKHWCEEGAS-SSSCSETYCGLYPESEPEVKAVASFLRR-NINQIKA 305

  Fly   301 YMAYHAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYGST-FTYGASGLLNYVVSGAA 364
            |::.|:|.|:::.||.::.:: ..::|::..:|:....|...:..:| :|:|......|:..|..
Human   306 YISMHSYSQHIVFPYSYTRSK-SKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGG 369

  Fly   365 KDWAY--GVKKIPFTCTVELRDKGTFGFFLPSNQITEVGLEVTAGLKAL 411
            .||.|  |:|   ::.|:||||.||:||.||...|.....|..|.:..:
Human   370 DDWIYDLGIK---YSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKI 415

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.