DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12374 and LOC1277609

DIOPT Version :10

Sequence 1:NP_610819.1 Gene:CG12374 / 36410 FlyBaseID:FBgn0033774 Length:422 Species:Drosophila melanogaster
Sequence 2:XP_317081.3 Gene:LOC1277609 / 1277609 VectorBaseID:AGAMI1_012293 Length:415 Species:Anopheles gambiae


Alignment Length:428 Identity:153/428 - (35%)
Similarity:228/428 - (53%) Gaps:28/428 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 KLPILLITLVAMVAAKSAPGRMAARYDHFRIYQLTIETNLQMEELKKIHEHISVH-----FLNEL 61
            ||.:||:..:|...:..     .||:|::|:|:::|||..|::.|    :|:.::     |....
Mosquito     4 KLTLLLVAAIAWGGSAE-----QARFDNYRVYEVSIETERQLKTL----QHLELNPDGYSFWESP 59

  Fly    62 GAVGNKYNVIVGPLFHRALEKTLKFLEIVYEVIVDDLQKLIDESSV--GDDSQMEWETYHTLDTI 124
            .....:.:::|.|......|:....|.:...:.::|.||:||....  ...:...|..|:|:|.|
Mosquito    60 VQTNMRLSIVVPPHKFAHFEELTVALALKTRLQIEDFQKVIDNERPMRSTRATFGWTDYYTVDEI 124

  Fly   125 YDWIDQECAAH-DFLECKVIGQSYEGRDIKSIRLSKRSGNKAIFLEGNIHAMEWISSATVTFLLN 188
            |.|:||..|.: ..|...|.|:|:||||:|:|:||.::||..||:|.||||.|||||||.|:|||
Mosquito   125 YAWMDQMVAQNPTILSGSVYGKSFEGRDLKAIKLSHKAGNPGIFIEANIHAREWISSATATWLLN 189

  Fly   189 QLINSEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNGYRNESGDCYGIDMNRNF 253
            :|:.|.:..:|.|::.|||..:.:.||||..|:....|.|||.|:|     .:..|.|.|.||||
Mosquito   190 ELVTSSNAAVQNLAQNYDWYFIMVANPDGLTYSKTTNRQWRKTRQP-----VNALCVGADPNRNF 249

  Fly   254 DYHW--GGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFVSSFEDGYIRSYMAYHAYGQYVLLPYG 316
            ||.|  |||.   ..||...|.|....:|.|..::.::.::..| .|....::|:||||:|.|:|
Mosquito   250 DYMWMTGGAS---SVPCSDTFAGLTAFSEPETKAMADYYATIAD-KINIQFSFHSYGQYLLTPFG 310

  Fly   317 HSNTEFPPNYEQMKRIAAAFSDAAADVYGSTFTYGASGLLNYVVSGAAKDWAYGVKKIPFTCTVE 381
            .|....|.|...::||||..:.|....||:.:|||.|..:.|..||:..|:..||.......|.|
Mosquito   311 FSGAPLPSNNADLQRIAAVTAAAIEATYGTRYTYGNSASVLYTTSGSTVDYFVGVHGTKLGFTFE 375

  Fly   382 LRDKGTFGFFLPSNQITEVGLEVTAGLKALVNKAAEEG 419
            .||.|..||.||:|||.....|...|:.|.|.:|...|
Mosquito   376 FRDTGATGFVLPANQIIPNAEETLNGIIAFVAEAKTLG 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12374NP_610819.1 Propep_M14 33..104 CDD:460505 16/75 (21%)
M14_CP_A-B_like 118..413 CDD:349433 123/297 (41%)
LOC1277609XP_317081.3 None

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