Protein Alignment Nacalpha and NACA2

DIOPT Version :9

• Sequence 1: NP_001286363.1
• Gene: Nacalpha / 36409
• FlyBaseID: FBgn0086904
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_954984.1
• Gene: NACA2 / 342538
• HGNCID: 23290
• Length: 215
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 120/214 - (56%)
• Similarity: 149/214 - (69%)
• Gaps: 10/214 - (4%)

  Fly     9 SEAAPSTSAEAKPEDVRVEDDGSDSDSDGGMPGLEE--AVAATTQLGGGATGLPID--LVSKAKQ 69
            :|..|:|..|. |:.......|:.|||...:||:||  :...|||.........||  .|.||||
Human     6 TETVPATEQEL-PQSQAETGSGTASDSGESVPGIEEQDSTQTTTQKAWLVAAAEIDEEPVGKAKQ 69

  Fly    70 SRGEKKARKIMLKLGLKQIQGVNRVTIRKSKNILFVINNPDVYKNPHSDTYIVFGEAKIEDLSQQ 134
            ||.||:|||.|.||||.|:.||.||||.|||||||||...||||:|.||.|||||||||:|||||
Human    70 SRSEKRARKAMSKLGLLQVTGVTRVTIWKSKNILFVITKLDVYKSPASDAYIVFGEAKIQDLSQQ 134

  Fly   135 AQVAAAEKFKAP-EAAGAADSVGATTSVAPIAEE-DEEDVDDTGVDEKDIELVITQANTTRAKAI 197
            ||:||||||:.. ||.|   ::...|....:.|| :||:||:|||:.||::||::|||.:||||:
Human   135 AQLAAAEKFRVQGEAVG---NIQENTQTPTVQEESEEEEVDETGVEVKDVKLVMSQANVSRAKAV 196

  Fly   198 KALKNNNNDIVNAIMELTM 216
            :|||||:|||||||||||:
Human   197 RALKNNSNDIVNAIMELTV 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nacalpha	NP_001286363.1	EGD2	74..216	CDD:224227	93/143 (65%)
		NAC	75..128	CDD:280093	38/52 (73%)
		UBA_NAC_euk	179..215	CDD:270541	25/35 (71%)
NACA2	NP_954984.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..51		16/45 (36%)
		NAC	82..128	CDD:307801	34/45 (76%)
		UBA_NACA_NACP1	174..214	CDD:270598	28/39 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	104	1.000	Domainoid score	I6694
eggNOG	1	0.900	-	-		E1_COG1308
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	203	1.000	Inparanoid score	I3752
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53634
OrthoDB	1	1.010	-	-		D1331328at2759
OrthoFinder	1	1.000	-	-		FOG0000996
OrthoInspector	1	1.000	-	-		otm41188
orthoMCL	1	0.900	-	-		OOG6_101216
Panther	1	1.100	-	-	O	PTHR21713
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2513
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.840