DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nacalpha and Nacad

DIOPT Version :9

Sequence 1:	NP_001286363.1	Gene:	Nacalpha / 36409	FlyBaseID:	FBgn0086904	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	XP_038947687.1	Gene:	Nacad / 289786	RGDID:	1559824	Length:	1696	Species:	Rattus norvegicus

Alignment Length:	213	Identity:	114/213 - (53%)
Similarity:	144/213 - (67%)	Gaps:	14/213 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 EAKPEDVRVED------DGSDSDSDGGMPG-LEEAVAATTQLGGGA---TGLPIDLVSKAKQSRG 72
            |.:.||...||      .|..|:|.|...| |:|...:..:....|   .|...:..:||||||.
  Rat  1484 EQEDEDSLEEDSQRAPGSGQHSESHGESSGELDEQDISPQKSQCPAQDPAGSNEETTAKAKQSRS 1548

  Fly    73 EKKARKIMLKLGLKQIQGVNRVTIRKSKNILFVINNPDVYKNPHSDTYIVFGEAKIEDLSQQAQV 137
            ||||||.|.||||:|||||.|:||:|||||||||..|||:|:|.||||:|||||||||||||...
  Rat  1549 EKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHK 1613

  Fly   138 AAAEKFKAP-EAAGAADSVGATTSVAPIA---EEDEEDVDDTGVDEKDIELVITQANTTRAKAIK 198
            |||||||.| |::.....:.....|.|..   ||:||:|::.|::.:|||||:.|||.:||||::
  Rat  1614 AAAEKFKVPSESSALVPELAPGPRVRPECEEQEEEEEEVEEAGLEPRDIELVMAQANVSRAKAVR 1678

  Fly   199 ALKNNNNDIVNAIMELTM 216
            |||:|::|||||||||||
  Rat  1679 ALKDNHSDIVNAIMELTM 1696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nacalpha	NP_001286363.1	EGD2	74..216	CDD:224227	91/145 (63%)
		NAC	75..128	CDD:280093	40/52 (77%)
		UBA_NAC_euk	179..215	CDD:270541	24/35 (69%)
Nacad	XP_038947687.1	PRK14949	<688..1044	CDD:237863
		PHA03247	<839..1385	CDD:223021
		NAC_NACA	1560..1607	CDD:409233	36/46 (78%)
		UBA_NACAD	1655..1696	CDD:270599	26/40 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340757
Domainoid	1	1.000	93	1.000	Domainoid score	I7376
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1331328at2759
OrthoFinder	1	1.000	-	-		FOG0000996
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21713
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.950