DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nacalpha and nacad

DIOPT Version :9

Sequence 1:	NP_001286363.1	Gene:	Nacalpha / 36409	FlyBaseID:	FBgn0086904	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	XP_012819673.1	Gene:	nacad / 100127557	XenbaseID:	XB-GENE-5961006	Length:	1937	Species:	Xenopus tropicalis

Alignment Length:	231	Identity:	118/231 - (51%)
Similarity:	149/231 - (64%)	Gaps:	18/231 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PELTEIKSEAAPSTSAEAKP-------EDVRVEDDGSDSDS-DGGMPGLEEAVAATTQLGGGATG 58
            ||:..::..:|.:.....||       |.:......:|::| |..:|.|||......:.......
Frog  1709 PEMHSLRETSAVTLLGITKPGPRQRGCESLSHRGSCNDTESNDESLPELEEPDVTEPRTSSSQNQ 1773

  Fly    59 LP------IDLVSKAKQSRGEKKARKIMLKLGLKQIQGVNRVTIRKSKNILFVINNPDVYKNPHS 117
            |.      .:.:|||||||.||||||.|.||||:||.||.|:||||||||||||..|||:|:|.|
Frog  1774 LAHCVAPGEESISKAKQSRSEKKARKAMSKLGLRQIHGVTRITIRKSKNILFVITKPDVFKSPAS 1838

  Fly   118 DTYIVFGEAKIEDLSQQAQVAAAEKFKAPEAAGAADSVGATTSVAPIAE--EDEEDVDDTGVDEK 180
            |.|||||||||||||||...|||||||.|  ...:..:..||....|.|  |:||:||:||::.:
Frog  1839 DIYIVFGEAKIEDLSQQVHKAAAEKFKVP--MEHSPLITETTPTLTIKEESEEEEEVDETGLEVR 1901

  Fly   181 DIELVITQANTTRAKAIKALKNNNNDIVNAIMELTM 216
            |||||:.|||.:||||::||::||||||||||||||
Frog  1902 DIELVMAQANVSRAKAVRALRHNNNDIVNAIMELTM 1937

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nacalpha	NP_001286363.1	EGD2	74..216	CDD:224227	94/143 (66%)
		NAC	75..128	CDD:280093	40/52 (77%)
		UBA_NAC_euk	179..215	CDD:270541	25/35 (71%)
nacad	XP_012819673.1	MSCRAMM_SdrC	<544..769	CDD:380146
		NAC	1796..1849	CDD:376630	40/52 (77%)
		UBA_NACAD	1894..1937	CDD:270599	29/42 (69%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	104	1.000	Domainoid score	I6616
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000996
OrthoInspector	1	1.000	-	-		otm48399
Panther	1	1.100	-	-	O	PTHR21713
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.010