Protein Alignment Dgkepsilon and Dgkz

DIOPT Version :10

• Sequence 1: NP_725228.1
• Gene: Dgkepsilon / 36408
• FlyBaseID: FBgn0020930
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001416441.1
• Gene: Dgkz / 81821
• RGDID: 70929
• Length: 1121
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 172/555 - (30%)
• Similarity: 256/555 - (46%)
• Gaps: 90/555 - (16%)

  Fly    39 FKTRHSWKSIKVLEQACFCNVCEILLTPSAGLFCDCCGLCTHATPPCQRRADR-EYRCKDKW--- 99
            |:|..|.....|.||.|   |.::|...:....|..|.:..|.  ||..:.:: .:|||..:
  Rat   293 FETNVSGDFCYVGEQYC---VAKMLPKSAPRRKCAACKIVVHT--PCIGQLEKINFRCKPSFRES 352

  Fly   100 ----LRNESSVRHLWVHGNLPMGVHCADC----NEEVDHHVSTDPGLYGWRCAWCQRCYHN--DC 154
                :|..:.|||.|||.....| .|..|    .::...|   ...:....|:||::.||:  .|
  Rat   353 GSRNVREPTFVRHHWVHRRRQDG-KCRHCGKGFQQKFTFH---SKEIVAISCSWCKQAYHSKVSC 413

  Fly   155 YTRADSMEACDLGEFKDMIFPPYSFVAAR------------TRDSMRLHLASITPPDIENW---- 203
            :......|.|.||....::.||...:.||            .|.|.: ..:|...|:...|
  Rat   414 FMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFK-RRSSKKGPEEGRWRPFI 477

  Fly   204 ---------EPLIVIANTKSGSSTGANVLSLLRGYLHPLQVMELGSRGPQDALQWAAKASPRPCR 259
                     :||:|..|.|||.:.||.::.....||:|.||.:|...||::||:...|.  ...|
  Rat   478 IRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPREALEMYRKV--HNLR 540

  Fly   260 ILVAGGDGTIGWVLNTIYTLNIKPQPSVAIMPLGTGNDLSRVLGWGA----EPPSVLDPVKILRS 320
            ||..|||||:||:|:|:..|.:||.|.|||:||||||||:|.|.||.    ||.|     |||..
  Rat   541 ILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVS-----KILSH 600

  Fly   321 IRRARSVNLDRFDLQIEKLHYRLPIQRHPTKT----IHVY-NYFSVGVDAYITYNFHKTRESRFY 380
            :.....|.|||:||:.|......|.:|....|    :.|: ||||:|.||::|..||::||:...
  Rat   601 VEEGNVVQLDRWDLRAEPNPEAGPEERDDGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPE 665

  Fly   381 LLSSRIFNKLLY-------FTFGTQQVMQPGCEHIE-----EKLTLYL-DNKPVQLPELQALVFL 432
            ..:||..||:.|       |..|:.:.:   .:||.     ..||..: |.||      |.:|||
  Rat   666 KFNSRFRNKMFYAGTAFSDFLMGSSKDL---AKHIRVVCDGMDLTPKIQDLKP------QCIVFL 721

  Fly   433 NIDSWGAGCKLCELSNANGEVRIVNSISDGMMEVFGIVSSFHIAQLQCNISKPVRIGQAKQIRLQ 497
            ||..:.||.........:.:.. .....||.:||.|...: .:|.||.. ....|:.|.:::.|.
  Rat   722 NIPRYCAGTMPWGHPGEHHDFE-PQRHDDGYLEVIGFTMT-SLAALQVG-GHGERLTQCREVLLT 783

  Fly   498 VKETVPMQADGEPWMQSPADIRLSSRSQARVLKLA 532
            ..:.:|:|.||||...:.:.||::.|:||.:::.|
  Rat   784 TAKAIPVQVDGEPCKLAASRIRIALRNQATMVQKA 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgkepsilon	NP_725228.1	C1_DGKepsilon_typeIII_rpt1	40..96	CDD:410351	14/56 (25%)
		C1_DGK_rpt2	108..167	CDD:410355	16/64 (25%)
		DAGKc	207..331	CDD:214487	57/127 (45%)
		DAGK_acc	356..510	CDD:459866	49/167 (29%)
Dgkz	NP_001416441.1	None