DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dgkepsilon and CG34384

DIOPT Version :9

Sequence 1:	NP_001286362.1	Gene:	Dgkepsilon / 36408	FlyBaseID:	FBgn0020930	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001246971.1	Gene:	CG34384 / 5740362	FlyBaseID:	FBgn0085413	Length:	1936	Species:	Drosophila melanogaster

Alignment Length:	446	Identity:	125/446 - (28%)
Similarity:	187/446 - (41%)	Gaps:	98/446 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EDFVSTFKT----------------------RHSWKSIKVLEQACFCNVCEILLT--PSAGLFCD 73
            ||::.:.||                      .|.|.:.. ..:..:||||...|:  .|.||.|:
  Fly   164 EDWLGSLKTATAPQRPRGDSFLIEQHDILSNHHHWYATS-HARPTYCNVCRDALSGVTSHGLSCE 227

  Fly    74 CCGLCTHATPPCQRRADREYRCKDKWLRN--------------ESS----VRHLWVHGNLPMGVH 120
            .|....|.            ||..|.:.|              |.:    :.|.|:.||||:...
  Fly   228 VCKCKVHK------------RCAAKSIANCKWTTLASVGKDIIEQADGIIMPHQWMEGNLPVSSM 280

  Fly   121 CADCNEEVDHHVSTDPGLYGWRCAWCQRCYHNDCYTRADSMEACDLGEFKDMIFPPYSFVAARTR 185
            ||.|.:.....:.    |..|||.||:...|..|  |.....||.:|..|..:.||.|..:..|.
  Fly   281 CAVCKKTCGSVLR----LQDWRCLWCRATVHVAC--RPQMAVACPIGPAKLSVVPPTSVHSISTD 339

  Fly   186 DSMRLHLASITPPDIENWEPLIVIANTKSGSSTGANVLSLLRGYLHPLQVMELGSRGPQDALQWA 250
            |:.     .:..|. .|:.||:|..|:|||.:.|...|...:..|:|.||.:|.|.||...|:..
  Fly   340 DAW-----DVASPK-GNFSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLISTGPSLGLRLF 398

  Fly   251 AKASPRPCRILVAGGDGTIGWVLNTIYTLNIKPQPSVAIMPLGTGNDLSRVLGWGAEPPSVLDPV 315
            ...  ...||||..|||::||||:.|...|:..|..||:|||||||||:||||||:.........
  Fly   399 RHF--EMFRILVCSGDGSVGWVLSEIDRFNMHKQCQVAVMPLGTGNDLARVLGWGSSCDDDTHLP 461

  Fly   316 KILRSIRRARSVNLDRFDLQI-EKLHYRLPIQRHPTKTIHVYNYFSVGVDAYIT-----YNFH-- 372
            :||.....|.:..|||:.:.: ||   .:|:.:.|..:|      |...:|.:|     .|.|
  Fly   462 QILERYESASTKMLDRWSIMVFEK---AIPVPKTPKMSI------STEQEAMLTGMVTSANHHLR 517

  Fly   373 ---KTRESRFYLLSSR--------IFNKLLYFTFGTQQVMQPGCEHIEEKLTLYLD 417
               :|.:::..:.|:|        :..::.......:| :...|:.:.:||.:.||
  Fly   518 FIVETNDTQTLIRSTRNLCDTVDDLVCRISEHHKDDEQ-LAVKCDILRQKLNMLLD 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dgkepsilon	NP_001286362.1	C1_1	108..165	CDD:278556	19/56 (34%)
		LCB5	207..519	CDD:224513	72/230 (31%)
		DAGKc	207..331	CDD:214487	51/123 (41%)
		DAGK_acc	355..510	CDD:279003	14/81 (17%)
CG34384	NP_001246971.1	PH	83..175	CDD:278594	4/10 (40%)
		PH_DGK_type2	84..180	CDD:270093	4/15 (27%)
		C1	196..245	CDD:197519	16/61 (26%)
		C1	268..318	CDD:197519	18/55 (33%)
		DAGKc	355..477	CDD:214487	51/123 (41%)
		DAGK_acc	1478..1635	CDD:279003
		SAM_DGK-delta-eta	1869..1933	CDD:188906
		SAM	1872..1935	CDD:197735
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462334
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16095at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11255
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950