Protein Alignment Dgkepsilon and si:dkey-172j4.3

DIOPT Version :10

• Sequence 1: NP_725228.1
• Gene: Dgkepsilon / 36408
• FlyBaseID: FBgn0020930
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_009301401.1
• Gene: si:dkey-172j4.3 / 565122
• ZFINID: ZDB-GENE-081104-24
• Length: 1100
• Species: Danio rerio
• Alignment Length: 780
• Identity: 177/780 - (22%)
• Similarity: 276/780 - (35%)
• Gaps: 282/780 - (36%)

  Fly     2 DIGTIELSVEALIGSLLALSILFAFCRSLL-------SEDFVSTFKTRHSWKSIKVLE------- 52
            |....|.|.:.:..|   .:::..|.:.:|       .||::|..|:...|::.:..:
Zfish   133 DASVAETSTKNINNS---FTVITPFRKLMLCAESRKEMEDWISALKSVQKWETYEASQFNMEHFS 194

  Fly    53 -----QAC------FCNVCEILL--TPSAGLFCDCCGLCTHATPPCQRRADREYRCKDKW----- 99
                 .||      |||||...|  ..|.||.|:.|....|..  |..|:..  .|  ||
Zfish   195 GMHNWYACSHARPTFCNVCREALPGVTSHGLSCEVCKFKAHKR--CAVRSTN--TC--KWTTLAS 253

  Fly   100 -----LRNES--SVRHLWVHGNLPMGVHCADCNEEVDHHVSTDPGLYGWRCAWCQRCYHNDCYTR 157
                 :.:|.  |:.|.|:.||||:...|..|    |.:..:...|..|||.||:...||.|  :
Zfish   254 IGNDIIEDEDGVSMPHQWLEGNLPVSAKCVVC----DRNCGSVRRLQDWRCLWCKAIVHNSC--K 312

  Fly   158 ADSMEACDLGEFKDMIFPPYSFVAARTRDSMRLHLASITPPDIENWEPLIVIANTKSGSSTGANV 222
            ....:.|.||:.|..|.||   .|..:.||.....|  |.|...:  ||:|:.|:|||.:.|...
Zfish   313 EQLGKVCPLGQCKVSIIPP---TALNSIDSDGFWKA--TSPSCSS--PLLVLVNSKSGDNQGVKF 370

  Fly   223 LSLLRGYLHPLQVMELGSRGPQDALQWAAKASPRPCRILVAGGDGTIGWVLNTIYTLNIKPQPSV 287
            |...:..|:|.||.:|.:.|||..|:...|.  ...|.||.||||::||||:.:..|::..|..:
Zfish   371 LRRFKQLLNPAQVFDLMNGGPQLGLRLFQKF--ETFRTLVCGGDGSVGWVLSELDKLSLHKQCQL 433

  Fly   288 AIMPLGTGNDLSRVLGWGAEPPSVLDPVKILRSIRRARSVNLDRFDL------------------ 334
            .::||||||||:||||||.........::||..:.||.:..|||:.:
Zfish   434 GVLPLGTGNDLARVLGWGGLCDDDAQLLQILEKLERATTKMLDRWSVMTYEVPTKQTPAIVKDDD 498

  Fly   335 ----------------------------------------------------------------- 334
                                                                             
Zfish   499 PSDSPLQITQYADSVATHLTKILDSDKHSDVISSAKFLCGTVNDFVAEVGKAYERATENKEEADA 563

  Fly   335 ----------------------------------------------------------------- 334
                                                                             
Zfish   564 MAKKCAMLNEKLDSLVKALSEDANAQLVPAGSISPDDSDTDQSRPFRSREQLMLRANSLKKALRQ 628

  Fly   335 ----------------QIEKLHYRLPIQR----------------HPTKTIHVY----------- 356
                            |::::.....|:|                .||.|..:.
Zfish   629 IIDQAEKVVDEQNRHTQVQRMSSTSSIKRGSSEDLKEAETRQNTLSPTATTPILLEKSESFGTVL 693

  Fly   357 ---------------NYFSVGVDAYITYNFHKTRESRFYLLSSRIFNKLLYFTFGTQQVMQPGCE 406
                           |||.:|:||.|:..|:..|:......|||..|.:.|...||::::|...:
Zfish   694 FSEESVQCTEKCVMNNYFGIGLDAKISLEFNNKRDENPKKCSSRTKNMMWYGVLGTKELVQKTYK 758

  Fly   407 HIEEKLTLYLDNKPVQLPELQALVFLNIDSWGAGCKLCELSNANGEVRIVN-----SISDGMMEV 466
            ::|:::.|..|...:.||.||.|..|||.|:..|.      |..|..:..|     |..|..:||
Zfish   759 NLEQRVQLECDGVSMSLPSLQGLAVLNIPSYAGGI------NFWGGTKEDNNFGAPSFDDKKLEV 817

  Fly   467 FGIVSSFHIAQLQCNISKPVRIGQAKQIRLQV--KETVPMQADGEPWMQSPADIRLSSRSQARVL 529
            ..:..|..:|..:....:..||.|.:|:::.:  .|.||:|.|||.|:|.|..:::..:::|::|
Zfish   818 VAVFGSMQMAMSRVINIQHHRIAQCRQVKITILGDEGVPVQVDGEAWIQPPGIVQIVHKNRAQML 882

  Fly   530  529
            Zfish   883  882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgkepsilon	NP_725228.1	C1_DGKepsilon_typeIII_rpt1	40..96	CDD:410351	18/75 (24%)
		C1_DGK_rpt2	108..167	CDD:410355	19/58 (33%)
		DAGKc	207..331	CDD:214487	49/123 (40%)
		DAGK_acc	356..510	CDD:459866	49/186 (26%)
si:dkey-172j4.3	XP_009301401.1	PH_DGK_type2	88..184	CDD:270093	11/53 (21%)
		C1	168..253	CDD:412127	24/90 (27%)
		C1	264..325	CDD:412127	22/66 (33%)
		DAGKc	355..477	CDD:214487	49/123 (40%)
		DAGKa	706..863	CDD:214486	49/162 (30%)