Protein Alignment Dgkepsilon and dgkb

DIOPT Version :10

• Sequence 1: NP_725228.1
• Gene: Dgkepsilon / 36408
• FlyBaseID: FBgn0020930
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_073779977.1
• Gene: dgkb / 557324
• ZFINID: ZDB-GENE-070126-1
• Length: 787
• Species: Danio rerio
• Alignment Length: 569
• Identity: 165/569 - (28%)
• Similarity: 234/569 - (41%)
• Gaps: 127/569 - (22%)

  Fly    42 RHSWKSIKVLEQACFCNVCEILL--TPSAGLFCDCCGLCTH------ATPPCQRRADREYRCKDK 98
            :|.|: :|...:..:||:|..:|  ....||.|..|....|      |.|.|.:.     ..|.|
Zfish   243 QHVWR-LKHFSKPAYCNLCLNMLIGLGKQGLCCSFCKYTVHERCVSRAPPSCIKT-----YVKSK 301

  Fly    99 WLRNESSVRHLWVHGNLPMGVHCADCNEEVDHHVSTDPGLYGWRCAWCQRCYHNDCYTRADSMEA 163
              :|...:.|.||.||.|.  .|..|::.:..:    .||.|..|.|||...||.|.:..  ...
Zfish   302 --KNTEIMHHFWVEGNCPS--KCDKCHKTIKCY----QGLTGLHCVWCQITLHNKCASHV--KPE 356

  Fly   164 CDLGEFKDMIFPPYSFV-----------------AARTR---------DSMRLHLASITPPDIEN 202
            ||.|..:|.|.||.:..                 ..||:         |...|   .|||  :|.
Zfish   357 CDCGSLRDHILPPNTICPVVLERQSTLRKDSNQSGGRTKIQRTNSVSVDGQGL---QITP--LEG 416

  Fly   203 WEPLIVIANTKSGSSTGANVLSLLRGYLHPLQVMELGSRGPQDALQWAAKASPRPCRILVAGGDG 267
            ..||:|..|.|||...|..:....:..|:|.||..|...||....        |.||
Zfish   417 THPLLVFVNPKSGGKQGERIFRKFQYLLNPRQVYNLAKSGPMPGY--------RSCR-------- 465

  Fly   268 TIGWV------------LNTI--YTL---NIKPQPSVAIMPLGTGNDLSRVLGWGA--EPPSVLD 313
            |:.:.            .|.:  |.|   |.:..|.|.::||||||||:|.|.||.  :..|:|
Zfish   466 TVEYYKTLCCPLAFSLSFNEVLFYFLDKANFEQNPPVCVLPLGTGNDLARCLHWGGGYDGESLL- 529

  Fly   314 PVKILRSIRRARSVNLDRFDLQIEKLHYRLPIQR----HPTKTIHVYNYFSVGVDAYITYNFHKT 374
              :||:.::.:..|.|||:.:.|      .|:.|    .|.....:.||||:||||.|.:.||..
Zfish   530 --QILKDVQDSSEVMLDRWKINI------TPVDRDEGGDPVPYSIINNYFSIGVDASIAHRFHIM 586

  Fly   375 RESRFYLLSSRIFNKLLYFTFGTQQVMQPGCEHIEEKLTLYLDNKPVQLP--ELQALVFLNIDSW 437
            ||......:||..|||.||.|||.:.....|:.:.:.|.:..|...:.|.  .|:.:..|||.|.
Zfish   587 REKHPERFNSRTKNKLWYFEFGTSETFSATCKKLHDYLEVECDGITLNLSNISLEGIAILNIPSM 651

  Fly   438 GAGCKLC-ELSNANGEVR--------------------IVNSISDGMMEVFGIVSSFHIAQLQCN 481
            ..|..|. |.....|..|                    .|...||.::||.|:..:..:.|:...
Zfish   652 HGGSNLWGESKKRRGHRRTGKKSPEKKTTIVDPKQLLFAVQDPSDQLLEVVGLEGAMEMGQIYTG 716

  Fly   482 I-SKPVRIGQAKQIRLQVKETVPMQADGEPWMQSPADIRLSSRSQARVL 529
            : |...|:.|...|.::..:::|||.|||||||||..|::...:|||:|
Zfish   717 LKSAGRRLAQCSSITIRTSKSLPMQIDGEPWMQSPCTIKIVHENQARML 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgkepsilon	NP_725228.1	C1_DGKepsilon_typeIII_rpt1	40..96	CDD:410351	15/61 (25%)
		C1_DGK_rpt2	108..167	CDD:410355	20/58 (34%)
		DAGKc	207..331	CDD:214487	41/142 (29%)
		DAGK_acc	356..510	CDD:459866	53/177 (30%)
dgkb	XP_073779977.1	None