Protein Alignment Dgkepsilon and Dgkk

DIOPT Version :9

• Sequence 1: NP_001286362.1
• Gene: Dgkepsilon / 36408
• FlyBaseID: FBgn0020930
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_038956233.1
• Gene: Dgkk / 367745
• RGDID: 1561510
• Length: 1385
• Species: Rattus norvegicus
• Alignment Length: 807
• Identity: 173/807 - (21%)
• Similarity: 277/807 - (34%)
• Gaps: 310/807 - (38%)

  Fly     5 TIELSVEALIGSLLALSILFAFC-------RSLLS------EDFVSTFKT--------------- 41
            ||:|| :.::......::...||       .||::      |::::..||
  Rat   369 TIDLS-QVVLAESSCRNLCHGFCVITPHRKVSLVAPSRQDMEEWINIIKTVQQGEIRQIPAAENN 432

  Fly    42 -----RHSWKSIKVLEQACFCNVC--EILLTPSAGLFCDCCGLCTHATPPCQRRADREYRCKDKW 99
                 .|.|.| ....:..|||||  .|.......:.|:.|.:.:|..  |..||:::  |  ||
  Rat   433 PFLIGMHYWYS-SPNPRTQFCNVCRENIPALSRDAIICEVCKVKSHKV--CALRANKD--C--KW 490

  Fly   100 LRNESSVR--------------HLWVHGNLPMGVHCADCNEEV-DHHVSTDPGLYGWRCAWCQRC 149
              |..|:.              |.||.||:|....|..|:|.. .:|     .|..:||.||...
  Rat   491 --NTLSITDDLLLPADEIQTMPHQWVEGNIPANSQCTVCHESCGSYH-----RLQDFRCLWCGST 548

  Fly   150 YHNDCYTRADSMEACDLGEFKDMIFPPYSFVAARTRDSMRLHLASITPPDIENWE---------P 205
            .|..|..|..  :.|..|..:.:|.||.:.  :..|...:|.::|      |.|.         |
  Rat   549 VHGACQKRFS--KECSFGSCRSLIVPPTAL--SDPRGDGQLVVSS------EFWNLDWPLTCSCP 603

  Fly   206 LIVIANTKSGSSTGANVLSLLRGYLHPLQVMELGSRGPQDALQWAAKASPRPCRILVAGGDGTIG 270
            |::..|:|||...|...|...:.||:|.||.:|...||:..:  |...:....|:||.||||::.
  Rat   604 LLIFINSKSGDHQGIIFLRKFKQYLNPSQVFDLAKGGPEAGI--AMFKNFARFRVLVCGGDGSVS 666

  Fly   271 WVLNTIYTLNIKPQPSVAIMPLGTGNDLSRVLGWGAEPPSVLDPVKILRSIRRARSVNLDRFDLQ 335
            |||:||....:..:..:||:||||||||:|||||||.......|::||..:.:|....|||:.:.
  Rat   667 WVLSTIDAYGLHDRCQMAIIPLGTGNDLARVLGWGAFWSKGKSPLEILSRVEQAHVRILDRWSVM 731

  Fly   336 IEKLHYRLPI--------------------------------QRHPTKTI--------------- 353
            |.:....:|:                                .::||:.:
  Rat   732 IRETPKPVPLLKGQVGMDIPRFEAAAIKNVESATTELNKILKAKYPTEMVIATRFLCSAVQDFID 796

  Fly   354 ----------------------------------------------------------------- 353
                                                                             
  Rat   797 DIVKAWHQIKQNTTAVESVILKSDLMYDKLSVLLDLLAEDAVAASAERTATAYGSRSKPDGKAFV 861

  Fly   354 ----------------------------------------------------------------- 353
                                                                             
  Rat   862 PELDHIAKAKMELAERAQKLQQSLKLILFQVEQVLDDESRQSLSVKNFASSLFLGDGDDDSDDYD 926

  Fly   354 -----------------------------HVY---------------NYFSVGVDAYITYNFHKT 374
                                         |::               |||.:|:||.|:..|:..
  Rat   927 QSPRHRSRCDTLSSIPSLRSEDLDNLDLEHLHVTPETIRFKERCVMNNYFGIGLDAKISLEFNAR 991

  Fly   375 RESRFYLLSSRIFNKLLYFTFGTQQVMQPGCEHIEEKLTLYLDNKPVQLPELQALVFLNIDSWGA 439
            ||......:||:.||:.|...|:::::|.....:||::.|..|.:.|.||.||.:|.|||.|:..
  Rat   992 REEHPEQYNSRLKNKIWYGLLGSKELLQRSYRKLEERIHLECDGEAVSLPNLQGIVVLNITSYAG 1056

  Fly   440 GCKLCELSNANGEVRIVNSISDGMMEVFGIVSSFHIAQLQCNISKPVRIGQAKQIRLQV--KETV 502
            |......:.|..|.. ..:|.||.:||..|..|..:|..:.......||.|.:::.:.:  :..:
  Rat  1057 GVNFWGSNTATTEYE-APAIDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCREVIITIDGEGGI 1120

  Fly   503 PMQADGEPWMQSPADIRLSSRSQARVL 529
            |:|.|||.|:|.|..|::..::.|::|
  Rat  1121 PVQVDGEAWIQKPGLIKIKYKNTAQML 1147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgkepsilon	NP_001286362.1	C1_1	108..165	CDD:278556	18/57 (32%)
		LCB5	207..519	CDD:224513	109/534 (20%)
		DAGKc	207..331	CDD:214487	49/123 (40%)
		DAGK_acc	355..510	CDD:279003	49/171 (29%)
Dgkk	XP_038956233.1	Trypan_PARP	<79..148	CDD:368653
		Trypan_PARP	<198..292	CDD:368653
		PH_DGK_type2	329..423	CDD:270093	11/54 (20%)
		C1_DGK_typeII_rpt1	437..494	CDD:410350	19/65 (29%)
		C1_DGK_typeII_rpt2	511..564	CDD:410402	19/59 (32%)
		DAGKc	605..727	CDD:214487	49/123 (40%)
		DAGKa	971..1128	CDD:214486	49/157 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349546
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840