Protein Alignment Dgkepsilon and Dgkk

DIOPT Version :9

• Sequence 1: NP_001286362.1
• Gene: Dgkepsilon / 36408
• FlyBaseID: FBgn0020930
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_808582.3
• Gene: Dgkk / 331374
• MGIID: 3580254
• Length: 1118
• Species: Mus musculus
• Alignment Length: 806
• Identity: 177/806 - (21%)
• Similarity: 278/806 - (34%)
• Gaps: 307/806 - (38%)

  Fly     5 TIELSVEALIGSLLALSILFAFC-------RSLLS------EDFVSTFKT--------------- 41
            ||:|| :.::......::...||       .||::      |::::..||
Mouse   100 TIDLS-QVVLAESSCRNLCHGFCVITPHRKVSLVAPTRQDMEEWINIIKTVQQGEIRQIPAAENN 163

  Fly    42 -----RHSWKSIKVLEQACFCNVC--EILLTPSAGLFCDCCGLCTHATPPCQRRADREYRCKDKW 99
                 .|.|.| ....::.|||||  .|.......:.|:.|.:.:|..  |..||:::  |  ||
Mouse   164 PFLVGMHYWYS-SSNPRSHFCNVCRENIPALSRDAVTCEVCQVKSHKF--CALRANKD--C--KW 221

  Fly   100 LRNESSVR--------------HLWVHGNLPMGVHCADCNEEV-DHHVSTDPGLYGWRCAWCQRC 149
              |..||.              |.||.||:|.|..|..|::.. .||     .|..:||.||...
Mouse   222 --NTLSVTDDLLLPADEIQTMPHQWVEGNIPAGSQCVVCHKSCGSHH-----RLQDFRCLWCGST 279

  Fly   150 YHNDCYTRADSMEACDLGEFKDMIFPPYSFVAARTRDSMRLHLASITPPDIEN--WE-----PLI 207
            .|..|..|..  :.|..|..:..|.||.:....|....:      :..||..|  |.     ||:
Mouse   280 VHGACQKRFS--KECSFGSRRSSIVPPTALSDPRGDGQL------VVSPDFWNLDWPLTCSCPLL 336

  Fly   208 VIANTKSGSSTGANVLSLLRGYLHPLQVMELGSRGPQDALQWAAKASPRPCRILVAGGDGTIGWV 272
            :..|:|||...|...|...:.||:|.||.:|...||:..:  |...:....|:||.||||::.||
Mouse   337 IFINSKSGDHQGIIFLRKFKQYLNPSQVFDLAKGGPEAGI--AMFKNFARFRVLVCGGDGSVSWV 399

  Fly   273 LNTIYTLNIKPQPSVAIMPLGTGNDLSRVLGWGAEPPSVLDPVKILRSIRRARSVNLDRFDLQIE 337
            |:||....:..:..:||:||||||||:|||||||.......|:.||..:.:|....|||:.:.|.
Mouse   400 LSTIDAYGLHDRCQLAIIPLGTGNDLARVLGWGAVWSKGTSPLDILSRVEQAHVRILDRWSVMIR 464

  Fly   338 KLHYRLPI--------------------------------QRHPTKTI----------------- 353
            :...:.|:                                .::||:.:
Mouse   465 ETPRQAPLLKGQVAMDIPRFEAAAIKNVESATTELNKILKAKYPTEMVIATRFLCSAVEDFVEDI 529

  Fly   354 ----------------------------------------------------------------- 353
                                                                             
Mouse   530 VKAWHQIKQNSTAVESVILKSDLMYDKLSVLIDLLAEDAVAASAERTATAYGSRSQADGKPFVPQ 594

  Fly   354 ----------------------------------------------------------------- 353
                                                                             
Mouse   595 LDHIARAKLELAERAQKLQQSLKLIIFQVEQVLDEESRQSLSVKNFTSSLFLGDGDDDDSDDYDQ 659

  Fly   354 ----------------------------HVY---------------NYFSVGVDAYITYNFHKTR 375
                                        |::               |||.:|:||.|:..|:..|
Mouse   660 SPRHRSRCDILCSIPSLRNEDLDNLDLEHLHIAPETIRFKEKCVMNNYFGIGLDAKISLEFNSRR 724

  Fly   376 ESRFYLLSSRIFNKLLYFTFGTQQVMQPGCEHIEEKLTLYLDNKPVQLPELQALVFLNIDSWGAG 440
            |......:||:.||:.|...|:::::|.....:||::.|..|.:.|.||.||.:|.|||.|:..|
Mouse   725 EEHPEQYNSRLKNKIWYGLLGSKELLQRSYRKLEERIHLECDGEAVSLPNLQGIVVLNITSYAGG 789

  Fly   441 CKLCELSNANGEVRIVNSISDGMMEVFGIVSSFHIAQLQCNISKPVRIGQAKQIRLQV--KETVP 503
            ......:.|..|.. |.:|:||.:||..|..|..:|..:....:..||.|..::.:.:  ::.||
Mouse   790 VNFWGRNRATTEYD-VPAINDGKLEVVAIFGSVQMAMSRIVNLQQHRIAQCHEVVITIDGEDGVP 853

  Fly   504 MQADGEPWMQSPADIRLSSRSQARVL 529
            :|.|||.|:|.|..|::..::.|::|
Mouse   854 VQVDGEAWIQKPGLIKIKYKNVAQML 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgkepsilon	NP_001286362.1	C1_1	108..165	CDD:278556	19/57 (33%)
		LCB5	207..519	CDD:224513	111/535 (21%)
		DAGKc	207..331	CDD:214487	49/123 (40%)
		DAGK_acc	355..510	CDD:279003	51/171 (30%)
Dgkk	NP_808582.3	PH	59..147	CDD:278594	9/47 (19%)
		PH_DGK_type2	60..154	CDD:270093	11/54 (20%)
		C1	170..219	CDD:237996	15/53 (28%)
		C1	242..292	CDD:237996	19/56 (34%)
		DAGKc	336..458	CDD:214487	49/123 (40%)
		DAGK_acc	703..860	CDD:295305	51/157 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846082
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840