Protein Alignment Dgkepsilon and Dgka

DIOPT Version :9

• Sequence 1: NP_001286362.1
• Gene: Dgkepsilon / 36408
• FlyBaseID: FBgn0020930
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_036011466.1
• Gene: Dgka / 13139
• MGIID: 102952
• Length: 788
• Species: Mus musculus
• Alignment Length: 553
• Identity: 182/553 - (32%)
• Similarity: 263/553 - (47%)
• Gaps: 84/553 - (15%)

  Fly    30 LLSEDFVSTFKTRHSWKSIKVLEQACFCNVCEILLT-PSAGLFCDCCGL-----CTHATPPCQRR 88
            ||..|........|.|:. |...:..:||:||..:: ...||.|:.|..     |.....||:..
Mouse   252 LLGMDVTMKDDGNHIWRP-KRFTRLVYCNLCEQSISLGKQGLSCNFCKYIVHDHCAMKAQPCEVS 315

  Fly    89 ADREYRCKDKWLRNESSVRHLWVHGNLPMGVHCADCNEEVDHHVSTDPGLYGWRCAWCQRCYHND 153
            ...:.| ||..:::     ||||.|    |.|...| :.....:.|...|.|..|.||....|:|
Mouse   316 TYAKSR-KDIGVQS-----HLWVRG----GCHSGRC-DRCQKKIRTYHSLTGLHCVWCHLEIHDD 369

  Fly   154 CYTRADSMEACDLGEFKDMIFPPYSFVAA----------RTRDSMRLHLASITPPD------IEN 202
            | .:|...| ||.|..:|.|.||.|...:          :|.|.     .|:..|:      :.|
Mouse   370 C-LQAVGPE-CDCGLLRDHILPPCSIYPSVLVSGQECKHKTTDD-----TSLCTPEAFRIEPVSN 427

  Fly   203 WEPLIVIANTKSGSSTGANVLSLLRGYLHPLQVMELGSRGPQDALQWAAKASPRPCRILVAGGDG 267
            ..||:|..|.|||...|.:||...:..|:|.||.:| ..||:..|:: .|..|: .||||.||||
Mouse   428 THPLLVFINLKSGGKQGQSVLWKFQYILNPRQVFDL-KDGPEPGLRF-FKDVPQ-FRILVCGGDG 489

  Fly   268 TIGWVLNTIYTLNIKPQPSVAIMPLGTGNDLSRVLGWGA--EPPSVLDPVKILRSIRRARSVNLD 330
            |:||||.||...|....|.||::||||||||:|.|.||.  |..::.   |||:.|..::.|.||
Mouse   490 TVGWVLETIDKANFATVPPVAVLPLGTGNDLARCLRWGRGYEGENLR---KILKDIELSKVVYLD 551

  Fly   331 RFDLQIEKLHYRLPIQR----HPTKTIHVYNYFSVGVDAYITYNFHKTRESRFYLLSSRIFNKLL 391
            |:.|::      :|.|.    .|..:..:.||||:||||.|.:.||..||......:||:.|||.
Mouse   552 RWFLEV------IPQQNGEKSDPVPSQIINNYFSIGVDASIAHRFHLMREKYPEKFNSRMKNKLW 610

  Fly   392 YFTFGTQQVMQPGCEHIEEKLTLYLDNKPVQLPE--LQALVFLNIDSWGAGCKL----------- 443
            ||.|.|.:.:...|:.:||.:|:.:..|.:.|.:  |:.:..|||.|...|..|
Mouse   611 YFEFATSESIFSTCKKLEESVTVEICGKLLDLSDLSLEGIAVLNIPSTHGGSNLWGDTKRPHGDT 675

  Fly   444 CELSNANGEV-----------RIVNSISDGMMEVFGIVSSFHIAQLQCNI-SKPVRIGQAKQIRL 496
            ||::.|.|..           ..|..:||..:||.||..:..:.|:...: |...|:.:..:|..
Mouse   676 CEINQALGSAAKIITDPDILKTCVPDMSDKRLEVVGIEGAIEMGQIYTRLKSAGHRLAKCSEITF 740

  Fly   497 QVKETVPMQADGEPWMQSPADIRLSSRSQARVL 529
            |..:|:|||.|||||||:|..|:::.::|..:|
Mouse   741 QTTKTLPMQIDGEPWMQAPCTIKITHKNQMPML 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgkepsilon	NP_001286362.1	C1_1	108..165	CDD:278556	19/56 (34%)
		LCB5	207..519	CDD:224513	125/342 (37%)
		DAGKc	207..331	CDD:214487	56/125 (45%)
		DAGK_acc	355..510	CDD:279003	57/179 (32%)
Dgka	XP_036011466.1	DAG_kinase_N	39..169	CDD:405237
		EFh	173..242	CDD:238008
		C1	260..320	CDD:412127	14/60 (23%)
		C1_DGKalpha_rpt2	329..390	CDD:410440	24/67 (36%)
		DAGKc	432..552	CDD:214487	56/125 (45%)
		DAGKa	573..754	CDD:214486	57/180 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000241
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810