Protein Alignment Dgkepsilon and LOC1274049

DIOPT Version :10

• Sequence 1: NP_725228.1
• Gene: Dgkepsilon / 36408
• FlyBaseID: FBgn0020930
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_313113.4
• Gene: LOC1274049 / 1274049
• VectorBaseID: AGAMI1_007133
• Length: 1438
• Species: Anopheles gambiae
• Alignment Length: 430
• Identity: 132/430 - (30%)
• Similarity: 201/430 - (46%)
• Gaps: 87/430 - (20%)

  Fly   178 SFVAARTRDSMRLHLASITPPDIE------NWEPLIVIANTKSGSSTGANVLSLLRGYLHPLQVM 236
            :|.|.|.......||..:..|:||      ..:||:|..|.|||...|..::|..|..|:|.||.
Mosquito   976 AFQALRESKYEEKHLLVLLLPNIEPSMVPAGVQPLLVFVNVKSGGCQGLELISSFRKLLNPYQVF 1040

  Fly   237 ELGSRGPQDALQWAAKASPRPCRILVAGGDGTIGWVLNTIYTLNIKPQ---PSVAIMPLGTGNDL 298
            :|.:.||...|.  .....:..:|||.||||||||||..:..:....:   |..||:||||||||
Mosquito  1041 DLDNGGPLPGLY--VFRHIQDYKILVCGGDGTIGWVLQCLDNVGQDSECSSPPCAIVPLGTGNDL 1103

  Fly   299 SRVLGWGAEPPSVLDPVKILRSIRRARSVNLDRFDL----------------------------- 334
            :|||.|||......||:.:||.:..|..:.|||:.:
Mosquito  1104 ARVLRWGAGYTGGEDPLNLLRDVIDAEEIRLDRWTVVFHPEDKPEDATPKAQPNSTGKKKKIQQQ 1168

  Fly   335 -----QIEKLHYRLPIQR------HPTKTI-----------------HVY---NYFSVGVDAYIT 368
                 |.::|..:...|:      ||:..|                 .::   |||.:|:||.:.
Mosquito  1169 QQQQQQQQQLQQQQQQQQQNQQHHHPSVAIVANPAQVVGGAQSEDNSQIFVMNNYFGIGIDADLC 1233

  Fly   369 YNFHKTRESRFYLLSSRIFNKLLYFTFGTQQVM-QPGCEHIEEKLTLYLDNKPVQLPELQALVFL 432
            .:||..||......:||:.||.:|...|.:::: :...:.:.::|.|.:|.|.|:||.::.::.|
Mosquito  1234 LDFHNAREENPNKFNSRLHNKGVYVKMGLRKMVGRKMVKELHKELRLEVDGKVVELPPVEGIIIL 1298

  Fly   433 NIDSWGAGC------KLCELSNANGEVRIVNSISDGMMEVFGIVSSFHIAQLQCNISKPVRIGQA 491
            ||.|||:|.      |..:.|..|.        .|||:||.|:....|:.|:|..:...:||.|.
Mosquito  1299 NILSWGSGANPWGPEKEDQFSKPNH--------WDGMLEVVGVTGVVHLGQIQSGLRSAMRIAQG 1355

  Fly   492 KQIRLQVKETVPMQADGEPWMQSPAD-IRLSSRSQARVLK 530
            ..|::.:...:|:|.|||||:|||.| :.|.|..:|.:||
Mosquito  1356 GHIKIHLHSDIPVQVDGEPWVQSPGDVVVLKSALKATMLK 1395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dgkepsilon	NP_725228.1	C1_DGKepsilon_typeIII_rpt1	40..96	CDD:410351
		C1_DGK_rpt2	108..167	CDD:410355
		DAGKc	207..331	CDD:214487	52/126 (41%)
		DAGK_acc	356..510	CDD:459866	50/163 (31%)
LOC1274049	XP_313113.4	C1_DGKtheta_typeV_rpt1	6..60	CDD:410353
		C1_DGKtheta_typeV_rpt2	64..120	CDD:410354
		C1_DGKtheta_typeV_rpt3	135..197	CDD:410404
		RA1_DAGK-theta	729..813	CDD:340631
		RA2_DAGK-theta	818..912	CDD:340481
		DAGKc	1011..1136	CDD:214487	52/126 (41%)
		DAGK_acc	1219..1374	CDD:459866	50/162 (31%)